BP

GO:0006658

phosphatidylserine metabolic process

The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes.

ISS

BP

GO:0006665

sphingolipid metabolic process

The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).

ISS

BP

GO:0008654

phospholipid biosynthetic process

The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.

IEA

BP

GO:0015825

L-serine transport

The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

ISS

BP

GO:1904219

positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity

Any process that activates or increases the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.

ISS

BP

GO:1904222

positive regulation of serine C-palmitoyltransferase activity

Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity.

ISS

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

ISS

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

ISS

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IBA

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0015194

L-serine transmembrane transporter activity

Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid.

IBA|ISS