Protein Description

Gene Symbol COG6
Entrez ID 57511
Uniprot ID Q9Y2V7
Description component of oligomeric golgi complex 6
Chromosomal Location chr13: 39,655,627-39,791,665
Ontology GO ID GO Term Definition Evidence

BP

GO:0006888

ER to Golgi vesicle-mediated transport

The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.

TAS

BP

GO:0006891

intra-Golgi vesicle-mediated transport

The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).

IBA

BP

GO:0015031

protein transport

The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

IEA

BP

GO:0070085

glycosylation

The covalent attachment and further modification of carbohydrate residues to a substrate molecule.

IMP

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

TAS

CC

GO:0017119

Golgi transport complex

A multisubunit tethering complex of the CATCHR family (complexes associated with tethering containing helical rods) that has a role in tethering vesicles to the Golgi prior to fusion. In yeast, this complex is called the Sec34/35 complex and is composed of eight subunits (Sec34p, Sec35p, Dor1p, Cod1p, Cod2p, Cod3p, Cod4p, and Cod5p). In mammals the subunits are named COG1-8.

IDA

CC

GO:0032588

trans-Golgi network membrane

The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.

TAS

Domain ID Description

IPR010490

Conserved oligomeric Golgi complex subunit 6

No pathways found.

UMLS CUI UMLS Term

C0020620

Hypohidrosis

Tissue Cell Type

adrenal gland

glandular cells

appendix

glandular cells

bone marrow

hematopoietic cells

bronchus

respiratory epithelial cells

cervix, uterine

squamous epithelial cells

colon

glandular cells

duodenum

glandular cells

epididymis

glandular cells

gallbladder

glandular cells

nasopharynx

respiratory epithelial cells

prostate

glandular cells

rectum

glandular cells

small intestine

glandular cells

spleen

cells in red pulp

stomach

glandular cells

testis

cells in seminiferous ducts

urinary bladder

urothelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

COG8

84342

Q96MW5

0.49

COG7

91949

P83436

0.59

COG4

25839

Q9H9E3

0.79

COG1

9382

Q8WTW3

0.59

COG5

10466

Q9UP83

0.59

COG2

22796

Q14746

0.59

CD68

968

P34810

0.63

EGFR

1956

P00533

0.63

ESR2

2100

Q92731

0.63

JUN

3725

P05412

0.63

ATXN7

6314

O15265

0.63

SCN2B

6327

O60939

0.63

UBD

10537

O15205

0.63

VSIG2

23584

Q96IQ7

0.63

PARP16

54956

Q8N5Y8

0.63

IFT57

55081

Q9NWB7

0.63

TRAPPC13

80006

A5PLN9

0.63

DTNBP1

84062

Q96EV8

0.63

COG3

83548

Q96JB2

0.89