| Gene Symbol | SCAF4 |
| Entrez ID | 57466 |
| Uniprot ID | O95104 |
| Description | SR-related CTD-associated factor 4 |
| Chromosomal Location | chr21: 31,671,033-31,732,075 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
CC | GO:0005654 | nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. | IDA |
MF | GO:0000166 | nucleotide binding |
Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. | IEA |
MF | GO:0044822 | poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. | IDA |
| Domain ID | Description |
|---|---|
IPR000504 | RNA recognition motif domain |
IPR006569 | CID domain |
IPR006903 | RNA polymerase II-binding domain |
IPR008942 | ENTH/VHS |
IPR034369 | SCAF4, RNA recognition motif |
| UMLS CUI | UMLS Term |
|---|---|
C0013080 | Down Syndrome |
C0151786 | Muscle Weakness |
| Tissue | Cell Type |
|---|---|
appendix | glandular cells |
bronchus | respiratory epithelial cells |
cerebellum | Purkinje cells |
cervix, uterine | glandular cells |
cervix, uterine | squamous epithelial cells |
colon | glandular cells |
duodenum | glandular cells |
epididymis | glandular cells |
esophagus | squamous epithelial cells |
gallbladder | glandular cells |
lymph node | germinal center cells |
nasopharynx | respiratory epithelial cells |
pancreas | exocrine glandular cells |
placenta | decidual cells |
placenta | trophoblastic cells |
rectum | glandular cells |
skin | keratinocytes |
skin | Langerhans |
small intestine | glandular cells |
stomach | glandular cells |
testis | cells in seminiferous ducts |
tonsil | germinal center cells |
tonsil | non-germinal center cells |
tonsil | squamous epithelial cells |
urinary bladder | urothelial cells |
vagina | squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
19141487 | Kenigsberg et al. | 2009 | Gene expression microarray profiles of cumulus cells in lean and overweightobese polycystic ovary syndrome patients |
22951915 | Haozi et al. | 2012 | Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
PLAUR | 5329 | Q03405 | 0.49 |
SH3BGRL | 6451 | O75368 | 0.49 |
SVIL | 6840 | O95425 | 0.49 |
UQCRFS1 | 7386 | P47985 | 0.49 |
VCL | 7414 | P18206 | 0.49 |
SUCLG2 | 8801 | Q96I99 | 0.49 |
VAPB | 9217 | O95292 | 0.49 |
CDK12 | 51755 | Q9NYV4 | 0.49 |
TXNDC17 | 84817 | Q9BRA2 | 0.49 |
SPTY2D1 | 144108 | Q68D10 | 0.49 |
VMA21 | 203547 | Q3ZAQ7 | 0.49 |
UQCRFS1P1 | 100128525 | P0C7P4 | 0.49 |
OXCT1 | 5019 | P55809 | 0.49 |
SELENBP1 | 8991 | Q13228 | 0.49 |
COA7 | 65260 | Q96BR5 | 0.49 |
BARD1 | 580 | Q99728 | 0.63 |
ELAVL1 | 1994 | Q15717 | 0.63 |
RPA1 | 6117 | P27694 | 0.63 |
RPA2 | 6118 | P15927 | 0.63 |
RPA3 | 6119 | P35244 | 0.63 |
TP63 | 8626 | Q9H3D4 | 0.63 |
EED | 8726 | O75530 | 0.63 |
OBSL1 | 23363 | O75147 | 0.63 |
QPRT | 23475 | Q15274 | 0.63 |
WWOX | 51741 | Q9NZC7 | 0.63 |
LUC7L | 55692 | Q9NQ29 | 0.63 |
MMS19 | 64210 | Q96T76 | 0.63 |
WBP4 | 11193 | O75554 | 0.68 |
CCNB2 | 9133 | O95067 | 0.72 |
PPP4R3A | 55671 | Q6IN85 | 0.72 |