Protein Description

Gene Symbol ERGIC1
Entrez ID 57222
Uniprot ID Q969X5
Description endoplasmic reticulum-golgi intermediate compartment 1
Chromosomal Location chr5: 172,834,275-172,952,685
Ontology GO ID GO Term Definition Evidence

BP

GO:0006888

ER to Golgi vesicle-mediated transport

The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.

IDA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

IEA

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

IEA

CC

GO:0005793

endoplasmic reticulum-Golgi intermediate compartment

A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi and Golgi-to-ER transport.

IDA

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

CC

GO:0033116

endoplasmic reticulum-Golgi intermediate compartment membrane

The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system.

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

Domain ID Description

IPR012936

Endoplasmic reticulum vesicle transporter, C-terminal

No pathways found.

No diseases found.

Tissue Cell Type

adrenal gland

glandular cells

appendix

glandular cells

bone marrow

hematopoietic cells

cerebellum

Purkinje cells

cerebral cortex

neuronal cells

colon

glandular cells

duodenum

glandular cells

epididymis

glandular cells

gallbladder

glandular cells

pancreas

exocrine glandular cells

placenta

decidual cells

prostate

glandular cells

rectum

glandular cells

seminal vesicle

glandular cells

skeletal muscle

myocytes

small intestine

glandular cells

smooth muscle

smooth muscle cells

stomach

glandular cells

testis

Leydig cells

thyroid gland

glandular cells

urinary bladder

urothelial cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

ATP6V1B1

525

P15313

0.49

GNAI2

2771

P04899

0.49

GOLGB1

2804

Q14789

0.49

ICT1

3396

Q14197

0.49

ITGA2

3673

P17301

0.49

NDUFV1

4723

P49821

0.49

UQCRFS1

7386

P47985

0.49

IST1

9798

P53990

0.49

FAF2

23197

Q96CS3

0.49

HIGD1A

25994

Q9Y241

0.49

TOMM7

54543

Q9P0U1

0.49

MRPL32

64983

Q9BYC8

0.49

MRPL11

65003

Q9Y3B7

0.49

EFNB1

1947

P98172

0.63

INA

9118

Q16352

0.63

TMED2

10959

Q15363

0.49

NTRK1

4914

P04629

0.63

RPA1

6117

P27694

0.63

RPA2

6118

P15927

0.63

RPA3

6119

P35244

0.63

SUMO2

6613

P61956

0.63

SUZ12

23512

Q15022

0.63

SYN1

6853

P17600

0.72

PRPF4

9128

O43172

0.72

CTR9

9646

Q6PD62

0.72

TFG

10342

Q92734

0.72

ERGIC3

51614

Q9Y282

0.77