| Gene Symbol | RALGAPA2 |
| Entrez ID | 57186 |
| Uniprot ID | Q2PPJ7 |
| Description | Ral GTPase activating protein, alpha subunit 2 (catalytic) |
| Chromosomal Location | chr20: 20,389,552-20,712,488 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0051056 |
regulation of small GTPase mediated signal transduction |
Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction. |
IEA |
|
BP |
GO:0090630 |
activation of GTPase activity |
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP. |
IBA|ISS |
|
CC |
GO:0005615 |
extracellular space |
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
IDA |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
|
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
IDA |
|
MF |
GO:0005096 |
GTPase activator activity |
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP. |
IBA|ISS |
|
MF |
GO:0046982 |
protein heterodimerization activity |
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer. |
ISS |
| Domain ID | Description |
|---|---|
|
IPR000331 |
Rap GTPase activating protein domain |
|
IPR011989 |
Armadillo-like helical |
|
IPR016024 |
Armadillo-type fold |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
cerebellum |
Purkinje cells |
|
cervix, uterine |
glandular cells |
|
colon |
endothelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
kidney |
cells in tubules |
|
liver |
bile duct cells |
|
liver |
hepatocytes |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
nasopharynx |
respiratory epithelial cells |
|
pancreas |
exocrine glandular cells |
|
pancreas |
islets of Langerhans |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
small intestine |
glandular cells |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
BRPF3 |
27154 |
Q9ULD4 |
0.63 |
|
GFOD1 |
54438 |
Q9NXC2 |
0.63 |
|
SPRTN |
83932 |
Q9H040 |
0.63 |
|
RALGAPB |
57148 |
Q86X10 |
0.75 |