| Gene Symbol | CHST7 |
| Entrez ID | 56548 |
| Uniprot ID | Q9NS84 |
| Description | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| Chromosomal Location | chrX: 46,573,784-46,598,408 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0005976 | polysaccharide metabolic process |
The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. | TAS |
BP | GO:0006044 | N-acetylglucosamine metabolic process |
The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. | IDA |
BP | GO:0006790 | sulfur compound metabolic process |
The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. | IDA |
BP | GO:0030206 | chondroitin sulfate biosynthetic process |
The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. | IDA|TAS |
CC | GO:0000139 | Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. | TAS |
CC | GO:0016021 | integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. | NAS|TAS |
MF | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity |
Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate. | IDA |
MF | GO:0008459 | chondroitin 6-sulfotransferase activity |
Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate. | IDA|TAS |
| Domain ID | Description |
|---|---|
IPR000863 | Sulfotransferase domain |
IPR016469 | Carbohydrate sulfotransferase |
IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
hsa00532 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | KEGG |
WP702 | Metapathway biotransformation | WikiPathways |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22617121 | Ouandaogo et al. | 2012 | Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22951915 | Haozi et al. | 2012 | Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
PEX19 | 5824 | P40855 | 0.63 |
GLT8D2 | 83468 | Q9H1C3 | 0.63 |