Protein Description

Gene Symbol CHST7
Entrez ID 56548
Uniprot ID Q9NS84
Description carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
Chromosomal Location chrX: 46,573,784-46,598,408
Ontology GO ID GO Term Definition Evidence

BP

GO:0005976

polysaccharide metabolic process

The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.

TAS

BP

GO:0006044

N-acetylglucosamine metabolic process

The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.

IDA

BP

GO:0006790

sulfur compound metabolic process

The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.

IDA

BP

GO:0030206

chondroitin sulfate biosynthetic process

The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.

IDA|TAS

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

TAS

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

NAS|TAS

MF

GO:0001517

N-acetylglucosamine 6-O-sulfotransferase activity

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate.

IDA

MF

GO:0008459

chondroitin 6-sulfotransferase activity

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.

IDA|TAS

Domain ID Description

IPR000863

Sulfotransferase domain

IPR016469

Carbohydrate sulfotransferase

IPR027417

P-loop containing nucleoside triphosphate hydrolase

Pathway ID Pathway Term Pathway Source

hsa00532

Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

KEGG

WP702

Metapathway biotransformation

WikiPathways

No diseases found.

No tissues found.

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

PEX19

5824

P40855

0.63

GLT8D2

83468

Q9H1C3

0.63