| Gene Symbol | CTPS2 |
| Entrez ID | 56474 |
| Uniprot ID | Q9NRF8 |
| Description | CTP synthase 2 |
| Chromosomal Location | chrX: 16,588,003-16,712,936 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006220 |
pyrimidine nucleotide metabolic process |
The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. |
TAS |
|
BP |
GO:0006541 |
glutamine metabolic process |
The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid. |
IEA |
|
BP |
GO:0015949 |
nucleobase-containing small molecule interconversion |
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule. |
TAS |
|
BP |
GO:0044210 |
de novo' CTP biosynthetic process |
The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components. |
IEA |
|
CC |
GO:0005739 |
mitochondrion |
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
IEA |
|
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
TAS |
|
MF |
GO:0003883 |
CTP synthase activity |
Catalysis of the reaction: ATP + UTP + NH3 = ADP + phosphate + CTP. |
EXP |
|
MF |
GO:0005524 |
ATP binding |
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR004468 |
CTP synthase |
|
IPR017456 |
CTP synthase, N-terminal |
|
IPR017926 |
Glutamine amidotransferase |
|
IPR027417 |
P-loop containing nucleoside triphosphate hydrolase |
|
IPR029062 |
Class I glutamine amidotransferase-like |
|
IPR033828 |
CTP synthase GATase domain |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa00240 |
Pyrimidine metabolism |
KEGG |
|
hsa01100 |
Metabolic pathways |
KEGG |
| Tissue | Cell Type |
|---|---|
|
appendix |
glandular cells |
|
cerebral cortex |
neuropil |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
lymph node |
germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
ovary |
follicle cells |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
small intestine |
glandular cells |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
tonsil |
germinal center cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
HSF1 |
3297 |
Q00613 |
0.63 |
|
RPL37A |
6168 |
P61513 |
0.63 |
|
MTMR2 |
8898 |
Q13614 |
0.63 |
|
PLIN3 |
10226 |
O60664 |
0.63 |
|
LRSAM1 |
90678 |
Q6UWE0 |
0.63 |
|
SPG21 |
51324 |
Q9NZD8 |
0.73 |
|
CTPS2 |
56474 |
Q9NRF8 |
0.79 |
|
COL9A1 |
1297 |
P20849 |
0.63 |
|
DHPS |
1725 |
P49366 |
0.63 |
|
FGFR1 |
2260 |
P11362 |
0.63 |
|
GTF2I |
2969 |
P78347 |
0.63 |
|
KTN1 |
3895 |
Q86UP2 |
0.63 |
|
METTL1 |
4234 |
Q9UBP6 |
0.63 |
|
MTNR1A |
4543 |
P48039 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
NUCB1 |
4924 |
Q02818 |
0.63 |
|
PRKDC |
5591 |
P78527 |
0.63 |
|
RNF2 |
6045 |
Q99496 |
0.63 |
|
RPL23A |
6147 |
P62750 |
0.63 |
|
SLAMF1 |
6504 |
Q13291 |
0.63 |
|
SUMO2 |
6613 |
P61956 |
0.63 |
|
WARS |
7453 |
P23381 |
0.63 |
|
XPO1 |
7514 |
O14980 |
0.63 |
|
EHD1 |
10938 |
Q9H4M9 |
0.63 |
|
EHD4 |
30844 |
Q9H223 |
0.63 |
|
ENPP6 |
133121 |
Q6UWR7 |
0.63 |
|
CTBP2 |
1488 |
P56545 |
0.70 |
|
NASP |
4678 |
P49321 |
0.72 |
|
SNX3 |
8724 |
O60493 |
0.72 |
|
OTUD5 |
55593 |
Q96G74 |
0.76 |