| Gene Symbol | CMAS |
| Entrez ID | 55907 |
| Uniprot ID | Q8NFW8 |
| Description | cytidine monophosphate N-acetylneuraminic acid synthetase |
| Chromosomal Location | chr12: 22,046,174-22,065,674 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006054 |
N-acetylneuraminate metabolic process |
The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid. |
IEA |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
TAS |
|
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
IBA |
|
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
|
MF |
GO:0008781 |
N-acylneuraminate cytidylyltransferase activity |
Catalysis of the reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate. |
IBA|TAS |
| Domain ID | Description |
|---|---|
|
IPR003329 |
Acylneuraminate cytidylyltransferase |
|
IPR023214 |
HAD-like domain |
|
IPR029044 |
Nucleotide-diphospho-sugar transferases |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa00520 |
Amino sugar and nucleotide sugar metabolism |
KEGG |
|
hsa01100 |
Metabolic pathways |
KEGG |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
breast |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
glial cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in granular layer |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
glial cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
colon |
endothelial cells |
|
colon |
glandular cells |
|
colon |
peripheral nerve/ganglion |
|
duodenum |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
heart muscle |
myocytes |
|
hippocampus |
glial cells |
|
hippocampus |
neuronal cells |
|
kidney |
cells in glomeruli |
|
kidney |
cells in tubules |
|
liver |
hepatocytes |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
pancreas |
exocrine glandular cells |
|
pancreas |
islets of Langerhans |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skeletal muscle |
myocytes |
|
skin |
melanocytes |
|
small intestine |
glandular cells |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
NAA15 |
80155 |
Q9BXJ9 |
0.49 |
|
DDB1 |
100290337 |
Q16531 |
0.49 |
|
APP |
351 |
P05067 |
0.56 |
|
NAA10 |
8260 |
P41227 |
0.49 |
|
HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI |
8339 |
P62807 |
0.49 |
|
HIST1H3A |
8350 |
P68431 |
0.49 |
|
SIGLEC12 |
89858 |
Q96PQ1 |
0.52 |
|
BRCA1 |
672 |
P38398 |
0.63 |
|
FGL1 |
2267 |
Q08830 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
LIMS1 |
3987 |
P48059 |
0.63 |
|
SUMO3 |
6612 |
P55854 |
0.63 |
|
SUMO2 |
6613 |
P61956 |
0.63 |
|
FIG4 |
9896 |
Q92562 |
0.63 |
|
FBXO6 |
26270 |
Q9NRD1 |
0.63 |
|
DBNL |
28988 |
Q9UJU6 |
0.63 |
|
LUC7L |
55692 |
Q9NQ29 |
0.63 |
|
COG3 |
83548 |
Q96JB2 |
0.63 |
|
LRRK2 |
120892 |
Q5S007 |
0.63 |