Gene Symbol | TMEM165 |
Entrez ID | 55858 |
Uniprot ID | Q9HC07 |
Description | transmembrane protein 165 |
Chromosomal Location | chr4: 55,395,957-55,453,397 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006487 |
protein N-linked glycosylation |
A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan. |
IMP |
BP |
GO:0006874 |
cellular calcium ion homeostasis |
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell. |
IGI |
BP |
GO:0032472 |
Golgi calcium ion transport |
The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus. |
IDA |
BP |
GO:0035751 |
regulation of lysosomal lumen pH |
Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion. |
IMP |
CC |
GO:0005765 |
lysosomal membrane |
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. |
IDA |
CC |
GO:0005794 |
Golgi apparatus |
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions. |
IDA |
CC |
GO:0010008 |
endosome membrane |
The lipid bilayer surrounding an endosome. |
IDA |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
CC |
GO:0031901 |
early endosome membrane |
The lipid bilayer surrounding an early endosome. |
IEA |
CC |
GO:0031902 |
late endosome membrane |
The lipid bilayer surrounding a late endosome. |
IEA |
CC |
GO:0032588 |
trans-Golgi network membrane |
The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network. |
IDA |
CC |
GO:0043231 |
intracellular membrane-bounded organelle |
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
IDA |
Domain ID | Description |
---|---|
IPR001727 |
Gdt1 family |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
appendix |
glandular cells |
bronchus |
respiratory epithelial cells |
cerebellum |
Purkinje cells |
cervix, uterine |
glandular cells |
colon |
glandular cells |
duodenum |
glandular cells |
endometrium |
glandular cells |
epididymis |
glandular cells |
fallopian tube |
glandular cells |
lymph node |
germinal center cells |
nasopharynx |
respiratory epithelial cells |
pancreas |
exocrine glandular cells |
pancreas |
islets of Langerhans |
placenta |
decidual cells |
placenta |
trophoblastic cells |
prostate |
glandular cells |
rectum |
glandular cells |
seminal vesicle |
glandular cells |
soft tissue |
chondrocytes |
stomach |
glandular cells |
testis |
Leydig cells |
tonsil |
germinal center cells |
tonsil |
squamous epithelial cells |
urinary bladder |
urothelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
REL |
5966 |
Q04864 |
0.63 |
AHSP |
51327 |
Q9NZD4 |
0.63 |
CALU |
813 |
O43852 |
0.49 |
MTHFD1 |
4522 |
P11586 |
0.49 |
RPLP1 |
6176 |
P05386 |
0.49 |
RPS26 |
6231 |
P62854 |
0.49 |
CUL3 |
8452 |
Q13618 |
0.63 |
SLC38A1 |
81539 |
Q9H2H9 |
0.63 |
CDK1 |
983 |
P06493 |
0.72 |
CNOT2 |
4848 |
Q9NZN8 |
0.72 |
CDK2AP1 |
8099 |
O14519 |
0.72 |
SMC3 |
9126 |
Q9UQE7 |
0.72 |
GPATCH8 |
23131 |
Q9UKJ3 |
0.72 |
SMC6 |
79677 |
Q96SB8 |
0.72 |
USP43 |
124739 |
Q70EL4 |
0.72 |