Protein Description

Gene Symbol CISD1
Entrez ID 55847
Uniprot ID Q9NZ45
Description CDGSH iron sulfur domain 1
Chromosomal Location chr10: 58,269,058-58,289,586
Ontology GO ID GO Term Definition Evidence

BP

GO:0043457

regulation of cellular respiration

Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds.

IEA

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

IDA|ISS

CC

GO:0005741

mitochondrial outer membrane

The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.

IEA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0046872

metal ion binding

Interacting selectively and non-covalently with any metal ion.

IEA

MF

GO:0051537

2 iron, 2 sulfur cluster binding

Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.

IEA

Domain ID Description

IPR018967

Iron sulphur-containing domain, CDGSH-type

IPR019610

Iron sulphur domain-containing, mitoNEET, N-terminal

Pathway ID Pathway Term Pathway Source

WP236

Adipogenesis

WikiPathways

No diseases found.

Tissue Cell Type

esophagus

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

25393639

Ambekar et al.

2014

Proteomics of follicular fluid from women with polycystic ovary syndrome suggests molecular defects in follicular development

Gene Symbol Entrez ID Uniprot ID Score

ATP6V1C1

528

P21283

0.49

CLTC

1213

Q00610

0.49

COX4I1

1327

P13073

0.49

MTX1

4580

Q13505

0.49

NDUFA2

4695

O43678

0.49

NR4A2

4929

P43354

0.49

PPIB

5479

P23284

0.49

RPL6

6128

Q02878

0.49

STX7

8417

O15400

0.49

BCAP31

10134

P51572

0.49

STX12

23673

Q86Y82

0.49

TOMM7

54543

Q9P0U1

0.49

NDUFA12

55967

Q9UI09

0.49

CISD1

55847

Q9NZ45

0.86

ANXA11

311

P50995

0.49

TSPO

706

P30536

0.49

PSMD7

5713

P51665

0.49

SDHB

6390

P21912

0.49

VDAC1

7416

P21796

0.49

VDAC2

7417

P45880

0.49

VDAC3

7419

Q9Y277

0.49

TECR

9524

Q9NZ01

0.49

TOMM40

10452

O96008

0.49

ATP5H

10476

O75947

0.49

PRKAB1

5564

Q9Y478

0.63

RNF2

6045

Q99496

0.63

ABCE1

6059

P61221

0.63

PARK2

5071

O60260

0.73