PCOSBase

Protein Description

Gene Symbol	LYAR
Entrez ID	55646
Uniprot ID	Q9NX58
Description	Ly1 antibody reactive
Chromosomal Location	chr4: 4,267,701-4,290,169

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Ontology	GO ID	GO Term	Definition	Evidence
CC	GO:0005634	nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	IDA
CC	GO:0005730	nucleolus	A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.	IDA
MF	GO:0005515	protein binding	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	IPI
MF	GO:0044822	poly(A) RNA binding	Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.	IDA
MF	GO:0046872	metal ion binding	Interacting selectively and non-covalently with any metal ion.	IEA

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Domain ID	Description
IPR013087	Zinc finger C2H2-type
IPR014898	Zinc finger, C2H2, LYAR-type

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No pathways found.

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No diseases found.

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Tissue	Cell Type
caudate	neuronal cells
cerebellum	cells in molecular layer
cerebellum	Purkinje cells
cerebral cortex	glial cells
cerebral cortex	neuronal cells
esophagus	squamous epithelial cells
kidney	cells in tubules
placenta	trophoblastic cells
skin	keratinocytes
skin	melanocytes
testis	cells in seminiferous ducts

No databases found.

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Pubmed ID	Author	Year	Title
22617121	Ouandaogo et al.	2012	Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

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Gene Symbol	Entrez ID	Uniprot ID	Score
ERCC4	2072	Q92889	0.49
ABCF1	23	Q8NE71	0.63
CIRBP	1153	Q14011	0.63
DKC1	1736	O60832	0.63
EIF2S1	1965	P05198	0.63
FBL	2091	P22087	0.63
FAU	2197	P35544	0.63
FUS	2521	P35637	0.63
HIST1H1D	3007	P16402	0.63
EIF6	3692	P56537	0.63
RPL24	6152	P83731	0.63
RPL26	6154	P61254	0.63
RPL28	6158	P46779	0.63
RPL32	6161	P62910	0.63
RPL36A	6173	P83881	0.63
RPS10	6204	P46783	0.63
RPS11	6205	P62280	0.63
RPS14	6208	P62263	0.63
RPS16	6217	P62249	0.63
RPS26	6231	P62854	0.63
SRPK1	6732	Q96SB4	0.63
SSB	6741	P05455	0.63
ZBTB16	7704	Q05516	0.63
HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI	8339	P62807	0.63
KRT36	8689	O76013	0.63
FGF18	8817	O76093	0.63
MAPKAPK2	9261	P49137	0.63
IGF2BP1	10642	Q9NZI8	0.63
HNRNPUL1	11100	Q9BUJ2	0.63
PWP1	11137	Q13610	0.63
RPL35	11224	P42766	0.63
RRP1B	23076	Q14684	0.63
RRS1	23212	Q15050	0.63
KPNA6	23633	O60684	0.63
RSL1D1	26156	O76021	0.63
GNL3	26354	Q9BVP2	0.63
PRPF19	27339	Q9UMS4	0.63
ANAPC2	29882	Q9UJX6	0.63
RSL24D1	51187	Q9UHA3	0.63
TMA16	55319	Q96EY4	0.63
NHP2	55651	Q9NX24	0.63
PPAN	56342	Q9NQ55	0.63
YTHDC2	64848	Q9H6S0	0.63
DDX54	79039	Q8TDD1	0.63
LBHD1	79081	Q9BQE6	0.63
C7orf50	84310	Q9BRJ6	0.63
MTDH	92140	Q86UE4	0.63
SRP9	653226	P49458	0.63
RPL21	6144	P46778	0.72
BRIX1	55299	Q8TDN6	0.72
PRKRA	8575	O75569	0.73
ZHX1	11244	Q9UKY1	0.73
BEND7	222389	Q8N7W2	0.73
DHX9	1660	Q08211	0.76
KPNA1	3836	P52294	0.76
KRT31	3881	Q15323	0.76
KRT82	3888	Q9NSB4	0.76
KRT85	3891	P78386	0.76
RPL3	6122	P39023	0.76
RPL18A	6142	Q02543	0.76
RPL23A	6147	P62750	0.76
RPS3A	6189	P61247	0.76
RPS9	6203	P46781	0.76
SRP14	6727	P37108	0.76
EIF3I	8668	Q13347	0.76
DDX21	9188	Q9NR30	0.76
EBNA1BP2	10969	Q99848	0.76
TWF2	11344	Q6IBS0	0.76
GTPBP4	23560	Q9BZE4	0.76
GNL2	29889	Q13823	0.76
NAT10	55226	Q9H0A0	0.76
DDX27	55661	Q96GQ7	0.76
TSR1	55720	Q2NL82	0.76
DHX57	90957	Q6P158	0.76
PHF6	84295	Q8IWS0	0.82
NPM1	4869	P06748	0.86
RPL31	6160	P62899	0.86
MYBBP1A	10514	Q9BQG0	0.86
CEP152	22995	O94986	0.49
CD2	914	P06729	0.63
ESR1	2099	P03372	0.63
ESR2	2100	Q92731	0.63
GRK5	2869	P34947	0.63
HDGF	3068	P51858	0.63
ILF2	3608	Q12905	0.63
JUN	3725	P05412	0.63
MNDA	4332	P41218	0.63
YBX1	4904	P67809	0.63
RNF2	6045	Q99496	0.63
SUMO3	6612	P55854	0.63
VCP	7415	P55072	0.63
CUL3	8452	Q13618	0.63
CUL1	8454	Q13616	0.63
MDC1	9656	Q14676	0.63
KIAA0101	9768	Q15004	0.63
COPS5	10987	Q92905	0.63
GABARAP	11337	O95166	0.63
GABARAPL2	11345	P60520	0.63
PAXIP1	22976	Q6ZW49	0.63
TNIK	23043	Q9UKE5	0.63
GABARAPL1	23710	Q9H0R8	0.63
AGO1	26523	Q9UL18	0.63
SDCBP2	27111	Q9H190	0.63
PHF20L1	51105	A8MW92	0.63
PRR11	55771	Q96HE9	0.63
CAND1	55832	Q86VP6	0.63
LLPH	84298	Q9BRT6	0.63
ADSSL1	122622	Q8N142	0.63
HNRNPU	3192	Q00839	0.72
NCBP1	4686	Q09161	0.72
OAS3	4940	Q9Y6K5	0.72
EIF2AK2	5610	P19525	0.72
RPL10	6134	P27635	0.72
EPB41L3	23136	Q9Y2J2	0.72
RFWD3	55159	Q6PCD5	0.72
FAM83H	286077	Q6ZRV2	0.72
TERF1	7013	P54274	0.73
TERF2	7014	Q15554	0.73
IFI16	3428	Q16666	0.82
NOP56	10528	O00567	0.82