Protein Description

Gene Symbol SYBU
Entrez ID 55638
Uniprot ID Q9NX95
Description syntabulin
Chromosomal Location chr8: 109,573,978-109,691,791
Ontology GO ID GO Term Definition Evidence

BP

GO:0061178

regulation of insulin secretion involved in cellular response to glucose stimulus

Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.

IEA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

IEA

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

IDA

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

IDA

CC

GO:0005874

microtubule

Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.

IDA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

CC

GO:0016023

cytoplasmic, membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

IEA

CC

GO:0031982

vesicle

Any small, fluid-filled, spherical organelle enclosed by membrane.

IDA

CC

GO:0043231

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

IDA

CC

GO:0097433

dense body

An electron dense body which may contain granules.

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0008017

microtubule binding

Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.

IEA

MF

GO:0017075

syntaxin-1 binding

Interacting selectively and non-covalently with the SNAP receptor syntaxin-1.

IEA

MF

GO:0019894

kinesin binding

Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.

IEA

Domain ID Description

IPR026198

Syntabulin

IPR028197

Syntaphilin/Syntabulin

No pathways found.

No diseases found.

No tissues found.

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

KIF5B

3799

P33176

0.52

DTNBP1

84062

Q96EV8

0.83

ATXN1

6310

P54253

0.63

FBXW11

23291

Q9UKB1

0.63

LARP1

23367

Q6PKG0

0.63

DISC1

27185

Q9NRI5

0.63

IFT57

55081

Q9NWB7

0.63

EXOC1

55763

Q9NV70

0.63

MAPRE1

22919

Q15691

0.72

RACGAP1

29127

Q9H0H5

0.72

RPL29

6159

P47914

0.73