BP

GO:0007275

multicellular organism development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

TAS

BP

GO:0021612

facial nerve structural organization

The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.

IEA

BP

GO:0021637

trigeminal nerve structural organization

The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.

IEA

BP

GO:0021766

hippocampus development

The progression of the hippocampus over time from its initial formation until its mature state.

IEA

BP

GO:0021785

branchiomotor neuron axon guidance

The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.

IBA

BP

GO:0021860

pyramidal neuron development

The progression of a pyramidal neuron from its initial formation to its mature state.

IEA

BP

GO:0030334

regulation of cell migration

Any process that modulates the frequency, rate or extent of cell migration.

IBA

BP

GO:0043087

regulation of GTPase activity

Any process that modulates the rate of GTP hydrolysis by a GTPase.

IEA

BP

GO:0048841

regulation of axon extension involved in axon guidance

Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance.

IBA

BP

GO:0048843

negative regulation of axon extension involved in axon guidance

Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance.

IEA

BP

GO:0050919

negative chemotaxis

The directed movement of a motile cell or organism towards a lower concentration of a chemical.

IEA

BP

GO:0051495

positive regulation of cytoskeleton organization

Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.

IEA

BP

GO:0071526

semaphorin-plexin signaling pathway

A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.

NAS

BP

GO:1902287

semaphorin-plexin signaling pathway involved in axon guidance

Any semaphorin-plexin signaling pathway that is involved in axon guidance.

IBA

BP

GO:1990138

neuron projection extension

Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.

IEA

CC

GO:0002116

semaphorin receptor complex

A stable binary complex of a neurophilin and a plexin, together forming a functional semaphorin receptor.

TAS

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

IDA|TAS

CC

GO:0005887

integral component of plasma membrane

The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IBA

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

TAS

CC

GO:0030054

cell junction

A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.

IDA

CC

GO:0043231

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

IDA

MF

GO:0004888

transmembrane signaling receptor activity

Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.

NAS

MF

GO:0017154

semaphorin receptor activity

Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

IBA