Gene Symbol | TRPV6 |
Entrez ID | 55503 |
Uniprot ID | Q9H1D0 |
Description | transient receptor potential cation channel, subfamily V, member 6 |
Chromosomal Location | chr7: 142,871,203-142,885,762 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006816 |
calcium ion transport |
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
IDA|NAS |
BP |
GO:0017158 |
regulation of calcium ion-dependent exocytosis |
Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis. |
NAS |
BP |
GO:0051592 |
response to calcium ion |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. |
ISS |
BP |
GO:0055074 |
calcium ion homeostasis |
Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell. |
ISS |
BP |
GO:0070588 |
calcium ion transmembrane transport |
A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. |
IDA|TAS |
BP |
GO:1990035 |
calcium ion import into cell |
The directed movement of calcium ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis. |
IDA|ISS |
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
IDA|TAS |
CC |
GO:0005887 |
integral component of plasma membrane |
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IDA|ISS|TAS |
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
MF |
GO:0005262 |
calcium channel activity |
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. |
IDA|TAS |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0005516 |
calmodulin binding |
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. |
IDA |
MF |
GO:0046872 |
metal ion binding |
Interacting selectively and non-covalently with any metal ion. |
IEA |
Domain ID | Description |
---|---|
IPR002110 |
Ankyrin repeat |
IPR004729 |
Transient receptor potential channel |
IPR005821 |
Ion transport domain |
IPR008344 |
Transient receptor potential cation channel subfamily V member 5/6 |
IPR008345 |
Transient receptor potential channel, vanilloid 6 |
IPR020683 |
Ankyrin repeat-containing domain |
IPR024862 |
Transient receptor potential cation channel subfamily V |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa04970 |
Salivary secretion |
KEGG |
hsa04978 |
Mineral absorption |
KEGG |
Tissue | Cell Type |
---|---|
placenta |
decidual cells |
soft tissue |
chondrocytes |
soft tissue |
fibroblasts |
Database Name |
---|
DisGeNET |
Pubmed ID | Author | Year | Title |
---|---|---|---|
21411543 |
Savaris et al. |
2011 |
Progesterone Resistance in PCOS Endometrium: A Microarray Analysis in Clomiphene Citrate-Treated and Artificial Menstrual Cycles |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
CALM2 |
805 |
P62158 |
0.62 |
CALM3 |
808 |
P62158 |
0.62 |
KRT40 |
125115 |
Q6A162 |
0.63 |
KRTAP10-5 |
386680 |
P60370 |
0.63 |
KRTAP10-8 |
386681 |
P60410 |
0.63 |
KRTAP10-3 |
386682 |
P60369 |
0.63 |
NOTCH2NL |
388677 |
Q7Z3S9 |
0.63 |
TRPV6 |
55503 |
Q9H1D0 |
0.65 |
NEDD4 |
4734 |
P46934 |
0.68 |
MDFI |
4188 |
Q99750 |
0.74 |
S100A10 |
6281 |
P60903 |
0.85 |
PRKCA |
5578 |
P17252 |
0.58 |
PDE9A |
5152 |
O76083 |
0.63 |
TRAF1 |
7185 |
Q13077 |
0.63 |
PNMA1 |
9240 |
Q8ND90 |
0.63 |
MID2 |
11043 |
Q9UJV3 |
0.63 |
CALB1 |
793 |
P05937 |
0.70 |
PTPN1 |
5770 |
P18031 |
0.94 |