| Gene Symbol | NCBP3 |
| Entrez ID | 55421 |
| Uniprot ID | Q53F19 |
| Description | nuclear cap binding subunit 3 |
| Chromosomal Location | chr17: 3,802,165-3,846,251 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006370 |
7-methylguanosine mRNA capping |
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript. |
IEA |
|
BP |
GO:0051028 |
mRNA transport |
The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
IEA |
|
BP |
GO:0051607 |
defense response to virus |
Reactions triggered in response to the presence of a virus that act to protect the cell or organism. |
IMP |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
|
CC |
GO:0034518 |
RNA cap binding complex |
Any protein complex that binds to a specialized RNA cap structure at any time in the lifetime of the RNA. |
TAS |
|
MF |
GO:0000166 |
nucleotide binding |
Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
IEA |
|
MF |
GO:0000340 |
RNA 7-methylguanosine cap binding |
Interacting selectively and non-covalently with the 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II. |
IMP |
|
MF |
GO:0003729 |
mRNA binding |
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
IDA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR019416 |
Nuclear cap-binding protein subunit 3 |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
bone marrow |
hematopoietic cells |
|
bronchus |
respiratory epithelial cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
endothelial cells |
|
colon |
glandular cells |
|
colon |
peripheral nerve/ganglion |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
kidney |
cells in tubules |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
ovarian stroma cells |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
skeletal muscle |
myocytes |
|
skin |
keratinocytes |
|
skin |
Langerhans |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
smooth muscle |
smooth muscle cells |
|
soft tissue |
adipocytes |
|
spleen |
cells in red pulp |
|
spleen |
cells in white pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
PLEC |
5339 |
Q15149 |
0.49 |
|
APP |
351 |
P05067 |
0.56 |
|
HNRNPH3 |
3189 |
P31942 |
0.63 |
|
SRPK2 |
6733 |
P78362 |
0.70 |
|
RPL6 |
6128 |
Q02878 |
0.72 |
|
RPL27 |
6155 |
P61353 |
0.72 |
|
SRP19 |
6728 |
P09132 |
0.72 |
|
SUPT5H |
6829 |
O00267 |
0.72 |
|
DDX39B |
7919 |
Q13838 |
0.72 |
|
THOC5 |
8563 |
Q13769 |
0.72 |
|
ZC3H11A |
9877 |
O75152 |
0.72 |
|
THOC1 |
9984 |
Q96FV9 |
0.72 |
|
ALYREF |
10189 |
Q86V81 |
0.72 |
|
DDX39A |
10212 |
O00148 |
0.72 |
|
CKAP2 |
26586 |
Q8WWK9 |
0.72 |
|
HP1BP3 |
50809 |
Q5SSJ5 |
0.72 |
|
WDR74 |
54663 |
Q6RFH5 |
0.72 |
|
PNO1 |
56902 |
Q9NRX1 |
0.72 |
|
THOC6 |
79228 |
Q86W42 |
0.72 |
|
FYTTD1 |
84248 |
Q96QD9 |
0.72 |
|
C19orf47 |
126526 |
Q8N9M1 |
0.72 |
|
CEP164 |
22897 |
Q9UPV0 |
0.49 |
|
BMI1 |
648 |
P35226 |
0.63 |
|
IFI16 |
3428 |
Q16666 |
0.63 |
|
NCBP1 |
4686 |
Q09161 |
0.63 |
|
RNF2 |
6045 |
Q99496 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
KIAA0101 |
9768 |
Q15004 |
0.63 |
|
OBSL1 |
23363 |
O75147 |
0.63 |
|
SUZ12 |
23512 |
Q15022 |
0.63 |
|
TRA2A |
29896 |
Q13595 |
0.63 |
|
RSRC1 |
51319 |
Q96IZ7 |
0.63 |
|
ARL6IP4 |
51329 |
Q66PJ3 |
0.63 |
|
LUC7L2 |
51631 |
Q9Y383 |
0.63 |
|
PRPF40A |
55660 |
O75400 |
0.63 |
|
NIFK |
84365 |
Q9BYG3 |
0.63 |
|
MYO1C |
4641 |
O00159 |
0.72 |
|
THOC2 |
57187 |
Q8NI27 |
0.72 |
|
THOC7 |
80145 |
Q6I9Y2 |
0.72 |
|
SUMO2 |
6613 |
P61956 |
0.73 |
|
SNIP1 |
79753 |
Q8TAD8 |
0.82 |