Protein Description

Gene Symbol PGM2
Entrez ID 55276
Uniprot ID Q96G03
Description phosphoglucomutase 2
Chromosomal Location chr4: 37,826,633-37,862,937
Ontology GO ID GO Term Definition Evidence

BP

GO:0005978

glycogen biosynthetic process

The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.

TAS

BP

GO:0005980

glycogen catabolic process

The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.

TAS

BP

GO:0006006

glucose metabolic process

The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.

IEA

BP

GO:0006098

pentose-phosphate shunt

The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.

TAS

BP

GO:0019388

galactose catabolic process

The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose.

TAS

BP

GO:0046386

deoxyribose phosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.

IEA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

IBA|TAS

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0000287

magnesium ion binding

Interacting selectively and non-covalently with magnesium (Mg) ions.

IEA

MF

GO:0004614

phosphoglucomutase activity

Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.

EXP

MF

GO:0008973

phosphopentomutase activity

Catalysis of the reaction: D-ribose 1-phosphate = D-ribose 5-phosphate.

IDA|TAS

Domain ID Description

IPR005841

Alpha-D-phosphohexomutase superfamily

IPR005843

Alpha-D-phosphohexomutase, C-terminal

IPR005844

Alpha-D-phosphohexomutase, alpha/beta/alpha domain I

IPR005845

Alpha-D-phosphohexomutase, alpha/beta/alpha domain II

IPR005846

Alpha-D-phosphohexomutase, alpha/beta/alpha domain III

IPR016055

Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III

IPR016066

Alpha-D-phosphohexomutase, conserved site

Pathway ID Pathway Term Pathway Source

hsa00010

Glycolysis / Gluconeogenesis

KEGG

hsa00030

Pentose phosphate pathway

KEGG

hsa00052

Galactose metabolism

KEGG

hsa00230

Purine metabolism

KEGG

hsa00500

Starch and sucrose metabolism

KEGG

hsa00520

Amino sugar and nucleotide sugar metabolism

KEGG

hsa01100

Metabolic pathways

KEGG

WP698

Glucuronidation

WikiPathways

No diseases found.

Tissue Cell Type

colon

endothelial cells

No databases found.

Pubmed ID Author Year Title

17148555

Wood et al.

2007

Molecular Abnormalities in Oocytes from Women with Polycystic Ovary Syndrome Revealed by Microarray Analysis

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

C11orf54

28970

Q9H0W9

0.49

HSPB1

3315

P04792

0.76

ABAT

18

P80404

0.49

MDH1

4190

P40925

0.49

TKT

7086

P29401

0.49

TPI1

7167

P60174

0.49

ALDH4A1

8659

P30038

0.49

PGM1

5236

P36871

0.59

ESR1

2099

P03372

0.63

NTRK1

4914

P04629

0.63

BAG3

9531

O95817

0.63

TERF1

7013

P54274

0.73

POT1

25913

Q9NUX5

0.73

ACD

65057

Q96AP0

0.73

TINF2

26277

Q9BSI4

0.75