Gene Symbol | PGM2 |
Entrez ID | 55276 |
Uniprot ID | Q96G03 |
Description | phosphoglucomutase 2 |
Chromosomal Location | chr4: 37,826,633-37,862,937 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0005978 |
glycogen biosynthetic process |
The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. |
TAS |
BP |
GO:0005980 |
glycogen catabolic process |
The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. |
TAS |
BP |
GO:0006006 |
glucose metabolic process |
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides. |
IEA |
BP |
GO:0006098 |
pentose-phosphate shunt |
The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses. |
TAS |
BP |
GO:0019388 |
galactose catabolic process |
The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose. |
TAS |
BP |
GO:0046386 |
deoxyribose phosphate catabolic process |
The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose. |
IEA |
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
IBA|TAS |
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
MF |
GO:0000287 |
magnesium ion binding |
Interacting selectively and non-covalently with magnesium (Mg) ions. |
IEA |
MF |
GO:0004614 |
phosphoglucomutase activity |
Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. |
EXP |
MF |
GO:0008973 |
phosphopentomutase activity |
Catalysis of the reaction: D-ribose 1-phosphate = D-ribose 5-phosphate. |
IDA|TAS |
Domain ID | Description |
---|---|
IPR005841 |
Alpha-D-phosphohexomutase superfamily |
IPR005843 |
Alpha-D-phosphohexomutase, C-terminal |
IPR005844 |
Alpha-D-phosphohexomutase, alpha/beta/alpha domain I |
IPR005845 |
Alpha-D-phosphohexomutase, alpha/beta/alpha domain II |
IPR005846 |
Alpha-D-phosphohexomutase, alpha/beta/alpha domain III |
IPR016055 |
Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III |
IPR016066 |
Alpha-D-phosphohexomutase, conserved site |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00010 |
Glycolysis / Gluconeogenesis |
KEGG |
hsa00030 |
Pentose phosphate pathway |
KEGG |
hsa00052 |
Galactose metabolism |
KEGG |
hsa00230 |
Purine metabolism |
KEGG |
hsa00500 |
Starch and sucrose metabolism |
KEGG |
hsa00520 |
Amino sugar and nucleotide sugar metabolism |
KEGG |
hsa01100 |
Metabolic pathways |
KEGG |
WP698 |
Glucuronidation |
WikiPathways |
Tissue | Cell Type |
---|---|
colon |
endothelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
17148555 |
Wood et al. |
2007 |
Molecular Abnormalities in Oocytes from Women with Polycystic Ovary Syndrome Revealed by Microarray Analysis |
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
C11orf54 |
28970 |
Q9H0W9 |
0.49 |
HSPB1 |
3315 |
P04792 |
0.76 |
ABAT |
18 |
P80404 |
0.49 |
MDH1 |
4190 |
P40925 |
0.49 |
TKT |
7086 |
P29401 |
0.49 |
TPI1 |
7167 |
P60174 |
0.49 |
ALDH4A1 |
8659 |
P30038 |
0.49 |
PGM1 |
5236 |
P36871 |
0.59 |
ESR1 |
2099 |
P03372 |
0.63 |
NTRK1 |
4914 |
P04629 |
0.63 |
BAG3 |
9531 |
O95817 |
0.63 |
TERF1 |
7013 |
P54274 |
0.73 |
POT1 |
25913 |
Q9NUX5 |
0.73 |
ACD |
65057 |
Q96AP0 |
0.73 |
TINF2 |
26277 |
Q9BSI4 |
0.75 |