| Gene Symbol | PHF10 |
| Entrez ID | 55274 |
| Uniprot ID | Q8WUB8 |
| Description | PHD finger protein 10 |
| Chromosomal Location | chr6: 169,703,905-169,725,566 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006351 |
transcription, DNA-templated |
The cellular synthesis of RNA on a template of DNA. |
IEA |
|
BP |
GO:0006355 |
regulation of transcription, DNA-templated |
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
IEA |
|
BP |
GO:0007399 |
nervous system development |
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. |
IEA |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
|
CC |
GO:0071564 |
npBAF complex |
A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. |
ISS |
|
MF |
GO:0008270 |
zinc ion binding |
Interacting selectively and non-covalently with zinc (Zn) ions. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR001965 |
Zinc finger, PHD-type |
|
IPR011011 |
Zinc finger, FYVE/PHD-type |
|
IPR013083 |
Zinc finger, RING/FYVE/PHD-type |
|
IPR019787 |
Zinc finger, PHD-finger |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
epididymis |
glandular cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
kidney |
cells in glomeruli |
|
kidney |
cells in tubules |
|
lung |
pneumocytes |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
pancreas |
islets of Langerhans |
|
placenta |
decidual cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
small intestine |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
urinary bladder |
urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
SMARCB1 |
6598 |
Q12824 |
0.49 |
|
LIG4 |
3981 |
P49917 |
0.63 |
|
NFKB1 |
4790 |
P19838 |
0.63 |
|
RELA |
5970 |
Q04206 |
0.63 |
|
SMARCA2 |
6595 |
P51531 |
0.73 |
|
SMARCA4 |
6597 |
P51532 |
0.73 |
|
SMARCC1 |
6599 |
Q92922 |
0.73 |
|
L3MBTL2 |
83746 |
Q969R5 |
0.73 |
|
ARID1A |
8289 |
O14497 |
0.49 |
|
APLP1 |
333 |
P51693 |
0.63 |
|
CELSR2 |
1952 |
Q9HCU4 |
0.63 |
|
SS18 |
6760 |
Q15532 |
0.63 |
|
VAV2 |
7410 |
P52735 |
0.63 |
|
HIST1H3A |
8350 |
P68431 |
0.63 |
|
UNC119 |
9094 |
Q13432 |
0.63 |
|
KIAA0101 |
9768 |
Q15004 |
0.63 |
|
SETDB1 |
9869 |
Q15047 |
0.63 |
|
STAM2 |
10254 |
O75886 |
0.63 |
|
NUP50 |
10762 |
Q9UKX7 |
0.63 |
|
UTP14A |
10813 |
Q9BVJ6 |
0.63 |
|
LUC7L |
55692 |
Q9NQ29 |
0.63 |
|
TRIM26 |
7726 |
Q12899 |
0.72 |
|
SMARCC2 |
6601 |
Q8TAQ2 |
0.73 |
|
SUMO2 |
6613 |
P61956 |
0.73 |
|
SMARCD1 |
6602 |
Q96GM5 |
0.74 |
|
SMARCE1 |
6605 |
Q969G3 |
0.74 |