| Gene Symbol | ATAD3A |
| Entrez ID | 55210 |
| Uniprot ID | Q9NVI7 |
| Description | ATPase family, AAA domain containing 3A |
| Chromosomal Location | chr1: 1,512,151-1,534,687 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0016049 |
cell growth |
The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. |
IMP |
|
BP |
GO:0043066 |
negative regulation of apoptotic process |
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. |
IMP |
|
CC |
GO:0005739 |
mitochondrion |
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
IDA |
|
CC |
GO:0005743 |
mitochondrial inner membrane |
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
IEA |
|
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
|
CC |
GO:0042645 |
mitochondrial nucleoid |
The region of a mitochondrion to which the DNA is confined. |
IEA |
|
MF |
GO:0005524 |
ATP binding |
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR003593 |
AAA+ ATPase domain |
|
IPR003959 |
ATPase, AAA-type, core |
|
IPR021911 |
ATPase family AAA domain-containing protein 3, domain of unknown function DUF3523 |
|
IPR027417 |
P-loop containing nucleoside triphosphate hydrolase |
| UMLS CUI | UMLS Term |
|---|---|
|
C0033578 |
Prostatic Neoplasms |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
cerebellum |
Purkinje cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
kidney |
cells in tubules |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
follicle cells |
|
pancreas |
exocrine glandular cells |
|
parathyroid gland |
glandular cells |
|
placenta |
trophoblastic cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
fibroblasts |
|
skin |
keratinocytes |
|
skin |
Langerhans |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
soft tissue |
chondrocytes |
|
spleen |
cells in red pulp |
|
spleen |
cells in white pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
COPB1 |
1315 |
P53618 |
0.49 |
|
NDUFB8 |
4714 |
O95169 |
0.49 |
|
NDUFS4 |
4724 |
O43181 |
0.49 |
|
RPN1 |
6184 |
P04843 |
0.49 |
|
SSR1 |
6745 |
P43307 |
0.49 |
|
VCP |
7415 |
P55072 |
0.49 |
|
PHB2 |
11331 |
Q99623 |
0.49 |
|
COA3 |
28958 |
Q9Y2R0 |
0.65 |
|
E2F3 |
1871 |
O00716 |
0.07 |
|
CYC1 |
1537 |
P08574 |
0.49 |
|
SLC25A3 |
5250 |
Q00325 |
0.49 |
|
UQCRC2 |
7385 |
P22695 |
0.49 |
|
ATP5L |
10632 |
O75964 |
0.49 |
|
POC5 |
134359 |
Q8NA72 |
0.49 |
|
GRB2 |
2885 |
P62993 |
0.56 |
|
ADRBK1 |
156 |
P25098 |
0.63 |
|
FMNL1 |
752 |
O95466 |
0.63 |
|
CDK2 |
1017 |
P24941 |
0.63 |
|
CDK9 |
1025 |
P50750 |
0.63 |
|
CSNK1A1 |
1452 |
P48729 |
0.63 |
|
CSNK1E |
1454 |
P49674 |
0.63 |
|
ERBB2 |
2064 |
P04626 |
0.63 |
|
FN1 |
2335 |
P02751 |
0.63 |
|
ICT1 |
3396 |
Q14197 |
0.63 |
|
ITGA4 |
3676 |
P13612 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
MCM2 |
4171 |
P49736 |
0.63 |
|
NFKB1 |
4790 |
P19838 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
PARK2 |
5071 |
O60260 |
0.63 |
|
PPP4C |
5531 |
P60510 |
0.63 |
|
PRKAA1 |
5562 |
Q13131 |
0.63 |
|
PRKACA |
5566 |
P17612 |
0.63 |
|
PRKACB |
5567 |
P22694 |
0.63 |
|
PRKCD |
5580 |
Q05655 |
0.63 |
|
RNF2 |
6045 |
Q99496 |
0.63 |
|
STK3 |
6788 |
Q13188 |
0.63 |
|
STK4 |
6789 |
Q13043 |
0.63 |
|
TP53 |
7157 |
P04637 |
0.63 |
|
GAN |
8139 |
Q9H2C0 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
CUL1 |
8454 |
Q13616 |
0.63 |
|
CEP57 |
9702 |
Q86XR8 |
0.63 |
|
KIAA0101 |
9768 |
Q15004 |
0.63 |
|
CUL7 |
9820 |
Q14999 |
0.63 |
|
PSMD6 |
9861 |
Q15008 |
0.63 |
|
OXSR1 |
9943 |
O95747 |
0.63 |
|
STK25 |
10494 |
O00506 |
0.63 |
|
TUBGCP2 |
10844 |
Q9BSJ2 |
0.63 |
|
OBSL1 |
23363 |
O75147 |
0.63 |
|
SRGAP2 |
23380 |
O75044 |
0.63 |
|
SUZ12 |
23512 |
Q15022 |
0.63 |
|
FBXO25 |
26260 |
Q8TCJ0 |
0.63 |
|
FBXO6 |
26270 |
Q9NRD1 |
0.63 |
|
SH3KBP1 |
30011 |
Q96B97 |
0.63 |
|
SIRT7 |
51547 |
Q9NRC8 |
0.63 |
|
WWOX |
51741 |
Q9NZC7 |
0.63 |
|
STK26 |
51765 |
Q9P289 |
0.63 |
|
LGR4 |
55366 |
Q9BXB1 |
0.63 |
|
RIOK2 |
55781 |
Q9BVS4 |
0.63 |
|
CCDC8 |
83987 |
Q9H0W5 |
0.63 |
|
ESR1 |
2099 |
P03372 |
0.67 |
|
PRPF40A |
55660 |
O75400 |
0.68 |
|
CFTR |
1080 |
P13569 |
0.72 |
|
HDGF |
3068 |
P51858 |
0.72 |
|
ILK |
3611 |
Q13418 |
0.72 |
|
MAP3K5 |
4217 |
Q99683 |
0.72 |
|
MLH1 |
4292 |
P40692 |
0.72 |
|
PHKG2 |
5261 |
P15735 |
0.72 |
|
PMS2 |
5395 |
P54278 |
0.72 |
|
TNFRSF1A |
7132 |
P19438 |
0.72 |
|
TNFRSF1B |
7133 |
P20333 |
0.72 |
|
TRADD |
8717 |
Q15628 |
0.72 |
|
AATK |
9625 |
Q6ZMQ8 |
0.72 |
|
HDAC6 |
10013 |
Q9UBN7 |
0.72 |
|
RIPK3 |
11035 |
Q9Y572 |
0.72 |
|
EPB41L3 |
23136 |
Q9Y2J2 |
0.72 |
|
WWC1 |
23286 |
Q8IX03 |
0.72 |
|
TUBA1C |
84790 |
Q9BQE3 |
0.72 |
|
PTP4A3 |
11156 |
O75365 |
0.76 |
|
BRF2 |
55290 |
Q9HAW0 |
0.76 |
|
C20orf24 |
55969 |
Q9BUV8 |
0.76 |
|
VCAM1 |
7412 |
P19320 |
0.82 |