| Gene Symbol | INTS10 |
| Entrez ID | 55174 |
| Uniprot ID | Q9NVR2 |
| Description | integrator complex subunit 10 |
| Chromosomal Location | chr8: 19,817,140-19,852,083 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0016180 |
snRNA processing |
Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. |
IDA |
|
BP |
GO:0042795 |
snRNA transcription from RNA polymerase II promoter |
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter. |
TAS |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
TAS |
|
CC |
GO:0032039 |
integrator complex |
A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II. |
IDA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
| Domain ID | Description |
|---|---|
|
IPR011990 |
Tetratricopeptide-like helical domain |
|
IPR026164 |
Integrator complex subunit 10 |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
bone marrow |
hematopoietic cells |
|
breast |
adipocytes |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
cervix, uterine |
glandular cells |
|
colon |
endothelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
heart muscle |
myocytes |
|
kidney |
cells in tubules |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
rectum |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skeletal muscle |
myocytes |
|
skin |
fibroblasts |
|
skin |
keratinocytes |
|
skin |
Langerhans |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
smooth muscle |
smooth muscle cells |
|
soft tissue |
chondrocytes |
|
soft tissue |
fibroblasts |
|
spleen |
cells in red pulp |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
POLR2A |
5430 |
P24928 |
0.63 |
|
POLR2B |
5431 |
P30876 |
0.63 |
|
POLR2D |
5433 |
O15514 |
0.63 |
|
POLR2E |
5434 |
P19388 |
0.63 |
|
POLR2H |
5437 |
P52434 |
0.63 |
|
RAF1 |
5894 |
P04049 |
0.63 |
|
INTS7 |
25896 |
Q9NVH2 |
0.63 |
|
CPSF3L |
54973 |
Q5TA45 |
0.63 |
|
INTS10 |
55174 |
Q9NVR2 |
0.63 |
|
INTS8 |
55656 |
Q75QN2 |
0.63 |
|
INTS9 |
55756 |
Q9NV88 |
0.63 |
|
INTS12 |
57117 |
Q96CB8 |
0.63 |
|
INTS4 |
92105 |
Q96HW7 |
0.63 |
|
INTS2 |
57508 |
Q9H0H0 |
0.73 |
|
POLR2C |
5432 |
P19387 |
0.63 |
|
SHFM1 |
7979 |
P60896 |
0.63 |
|
HDGF |
3068 |
P51858 |
0.72 |
|
PPP2CA |
5515 |
P67775 |
0.72 |
|
VWA9 |
81556 |
Q96SY0 |
0.72 |
|
INTS1 |
26173 |
Q8N201 |
0.73 |
|
INTS6 |
26512 |
Q9UL03 |
0.73 |
|
INTS3 |
65123 |
Q68E01 |
0.73 |
|
INTS5 |
80789 |
Q6P9B9 |
0.73 |