| Gene Symbol | INTS10 |
| Entrez ID | 55174 |
| Uniprot ID | Q9NVR2 |
| Description | integrator complex subunit 10 |
| Chromosomal Location | chr8: 19,817,140-19,852,083 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0016180 | snRNA processing |
Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. | IDA |
BP | GO:0042795 | snRNA transcription from RNA polymerase II promoter |
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter. | TAS |
CC | GO:0005654 | nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. | TAS |
CC | GO:0032039 | integrator complex |
A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II. | IDA |
MF | GO:0005515 | protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). | IPI |
| Domain ID | Description |
|---|---|
IPR011990 | Tetratricopeptide-like helical domain |
IPR026164 | Integrator complex subunit 10 |
| Tissue | Cell Type |
|---|---|
adrenal gland | glandular cells |
bone marrow | hematopoietic cells |
breast | adipocytes |
breast | glandular cells |
breast | myoepithelial cells |
bronchus | respiratory epithelial cells |
cervix, uterine | glandular cells |
colon | endothelial cells |
colon | glandular cells |
duodenum | glandular cells |
endometrium | glandular cells |
fallopian tube | glandular cells |
gallbladder | glandular cells |
heart muscle | myocytes |
kidney | cells in tubules |
lymph node | non-germinal center cells |
nasopharynx | respiratory epithelial cells |
rectum | glandular cells |
seminal vesicle | glandular cells |
skeletal muscle | myocytes |
skin | fibroblasts |
skin | keratinocytes |
skin | Langerhans |
skin | epidermal cells |
small intestine | glandular cells |
smooth muscle | smooth muscle cells |
soft tissue | chondrocytes |
soft tissue | fibroblasts |
spleen | cells in red pulp |
testis | Leydig cells |
thyroid gland | glandular cells |
tonsil | germinal center cells |
tonsil | non-germinal center cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22951915 | Haozi et al. | 2012 | Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
POLR2A | 5430 | P24928 | 0.63 |
POLR2B | 5431 | P30876 | 0.63 |
POLR2D | 5433 | O15514 | 0.63 |
POLR2E | 5434 | P19388 | 0.63 |
POLR2H | 5437 | P52434 | 0.63 |
RAF1 | 5894 | P04049 | 0.63 |
INTS7 | 25896 | Q9NVH2 | 0.63 |
CPSF3L | 54973 | Q5TA45 | 0.63 |
INTS10 | 55174 | Q9NVR2 | 0.63 |
INTS8 | 55656 | Q75QN2 | 0.63 |
INTS9 | 55756 | Q9NV88 | 0.63 |
INTS12 | 57117 | Q96CB8 | 0.63 |
INTS4 | 92105 | Q96HW7 | 0.63 |
INTS2 | 57508 | Q9H0H0 | 0.73 |
POLR2C | 5432 | P19387 | 0.63 |
SHFM1 | 7979 | P60896 | 0.63 |
HDGF | 3068 | P51858 | 0.72 |
PPP2CA | 5515 | P67775 | 0.72 |
VWA9 | 81556 | Q96SY0 | 0.72 |
INTS1 | 26173 | Q8N201 | 0.73 |
INTS6 | 26512 | Q9UL03 | 0.73 |
INTS3 | 65123 | Q68E01 | 0.73 |
INTS5 | 80789 | Q6P9B9 | 0.73 |