Protein Description

Gene Symbol AURKAIP1
Entrez ID 54998
Uniprot ID Q9NWT8
Description aurora kinase A interacting protein 1
Chromosomal Location chr1: 1,373,730-1,375,495
Ontology GO ID GO Term Definition Evidence

BP

GO:0006397

mRNA processing

Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.

IBA

BP

GO:0045839

negative regulation of mitotic nuclear division

Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.

NAS

BP

GO:0045862

positive regulation of proteolysis

Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.

IDA

BP

GO:0070125

mitochondrial translational elongation

The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.

TAS

BP

GO:0070126

mitochondrial translational termination

The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).

TAS

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

IDA

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

IBA|IDA

CC

GO:0005743

mitochondrial inner membrane

The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

TAS

CC

GO:0043231

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

IDA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

Domain ID Description

IPR013177

Domain of unknown function DUF1713

No pathways found.

No diseases found.

Tissue Cell Type

bronchus

respiratory epithelial cells

caudate

glial cells

cerebellum

Purkinje cells

cerebral cortex

glial cells

cerebral cortex

neuronal cells

colon

glandular cells

duodenum

glandular cells

epididymis

glandular cells

esophagus

squamous epithelial cells

nasopharynx

respiratory epithelial cells

placenta

trophoblastic cells

rectum

glandular cells

skin

keratinocytes

skin

melanocytes

skin

epidermal cells

stomach

glandular cells

urinary bladder

urothelial cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

AURKAIP1

54998

Q9NWT8

0.55

CEP131

22994

Q9UPN4

0.63

FAM9B

171483

Q8IZU0

0.63

AURKA

6790

O14965

0.86

NUP43

348995

Q8NFH3

0.49

CDK2

1017

P24941

0.63

CUL3

8452

Q13618

0.63

CNOT1

23019

A5YKK6

0.72

GEMIN7

79760

Q9H840

0.72