Gene Symbol | AURKAIP1 |
Entrez ID | 54998 |
Uniprot ID | Q9NWT8 |
Description | aurora kinase A interacting protein 1 |
Chromosomal Location | chr1: 1,373,730-1,375,495 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006397 |
mRNA processing |
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. |
IBA |
BP |
GO:0045839 |
negative regulation of mitotic nuclear division |
Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. |
NAS |
BP |
GO:0045862 |
positive regulation of proteolysis |
Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. |
IDA |
BP |
GO:0070125 |
mitochondrial translational elongation |
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion. |
TAS |
BP |
GO:0070126 |
mitochondrial translational termination |
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa). |
TAS |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA |
CC |
GO:0005739 |
mitochondrion |
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
IBA|IDA |
CC |
GO:0005743 |
mitochondrial inner membrane |
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
TAS |
CC |
GO:0043231 |
intracellular membrane-bounded organelle |
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
IDA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
Domain ID | Description |
---|---|
IPR013177 |
Domain of unknown function DUF1713 |
Tissue | Cell Type |
---|---|
bronchus |
respiratory epithelial cells |
caudate |
glial cells |
cerebellum |
Purkinje cells |
cerebral cortex |
glial cells |
cerebral cortex |
neuronal cells |
colon |
glandular cells |
duodenum |
glandular cells |
epididymis |
glandular cells |
esophagus |
squamous epithelial cells |
nasopharynx |
respiratory epithelial cells |
placenta |
trophoblastic cells |
rectum |
glandular cells |
skin |
keratinocytes |
skin |
melanocytes |
skin |
epidermal cells |
stomach |
glandular cells |
urinary bladder |
urothelial cells |
vagina |
squamous epithelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
AURKAIP1 |
54998 |
Q9NWT8 |
0.55 |
CEP131 |
22994 |
Q9UPN4 |
0.63 |
FAM9B |
171483 |
Q8IZU0 |
0.63 |
AURKA |
6790 |
O14965 |
0.86 |
NUP43 |
348995 |
Q8NFH3 |
0.49 |
CDK2 |
1017 |
P24941 |
0.63 |
CUL3 |
8452 |
Q13618 |
0.63 |
CNOT1 |
23019 |
A5YKK6 |
0.72 |
GEMIN7 |
79760 |
Q9H840 |
0.72 |