| Gene Symbol | DDX49 |
| Entrez ID | 54555 |
| Uniprot ID | Q9Y6V7 |
| Description | DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 |
| Chromosomal Location | chr19: 18,919,675-18,928,633 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006364 |
rRNA processing |
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
TAS |
|
BP |
GO:0010501 |
RNA secondary structure unwinding |
The process in which a secondary structure of RNA are broken or 'melted'. |
IBA |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
TAS |
|
MF |
GO:0004004 |
ATP-dependent RNA helicase activity |
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix. |
IBA |
|
MF |
GO:0005524 |
ATP binding |
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
IEA |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR000629 |
ATP-dependent RNA helicase DEAD-box, conserved site |
|
IPR001650 |
Helicase, C-terminal |
|
IPR011545 |
DEAD/DEAH box helicase domain |
|
IPR014001 |
Helicase superfamily 1/2, ATP-binding domain |
|
IPR014014 |
RNA helicase, DEAD-box type, Q motif |
|
IPR027417 |
P-loop containing nucleoside triphosphate hydrolase |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
gallbladder |
glandular cells |
|
kidney |
cells in tubules |
|
lung |
macrophages |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
parathyroid gland |
glandular cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
fibroblasts |
|
small intestine |
glandular cells |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
urinary bladder |
urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
PNO1 |
56902 |
Q9NRX1 |
0.49 |
|
HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI |
8339 |
P62807 |
0.49 |
|
NSUN2 |
54888 |
Q08J23 |
0.49 |
|
APP |
351 |
P05067 |
0.56 |
|
JUN |
3725 |
P05412 |
0.63 |
|
PSMB2 |
5690 |
P49721 |
0.63 |
|
HAP1 |
9001 |
P54257 |
0.73 |