PCOSBase

Protein Description

Gene Symbol	MRPL50
Entrez ID	54534
Uniprot ID	Q8N5N7
Description	mitochondrial ribosomal protein L50
Chromosomal Location	chr9: 101,387,633-101,398,614

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Ontology	GO ID	GO Term	Definition	Evidence
BP	GO:0070125	mitochondrial translational elongation	The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.	TAS
BP	GO:0070126	mitochondrial translational termination	The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).	TAS
CC	GO:0005743	mitochondrial inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.	TAS
CC	GO:0005840	ribosome	An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.	IEA

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Domain ID	Description
IPR018305	Ribosomal protein L50, mitochondria

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No pathways found.

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No diseases found.

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Tissue	Cell Type
adrenal gland	glandular cells
appendix	glandular cells
appendix	lymphoid tissue
bronchus	respiratory epithelial cells
caudate	glial cells
cerebellum	Purkinje cells
colon	glandular cells
duodenum	glandular cells
esophagus	squamous epithelial cells
gallbladder	glandular cells
hippocampus	glial cells
kidney	cells in tubules
liver	hepatocytes
lung	macrophages
parathyroid gland	glandular cells
rectum	glandular cells
small intestine	glandular cells
smooth muscle	smooth muscle cells
spleen	cells in white pulp
stomach	glandular cells
testis	Leydig cells
tonsil	non-germinal center cells
tonsil	squamous epithelial cells
urinary bladder	urothelial cells

No databases found.

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Pubmed ID	Author	Year	Title
23824412	Piltonen et al.	2013	Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential

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Gene Symbol	Entrez ID	Uniprot ID	Score
ATP6V1B1	525	P15313	0.49
ATP6V0A1	535	Q93050	0.49
SUCLG2	8801	Q96I99	0.49
TSR1	55720	Q2NL82	0.49
MRPS9	64965	P82933	0.49
MRPL57	78988	Q9BQC6	0.49
TMEM177	80775	Q53S58	0.49
SLC25A10	1468	Q9UBX3	0.63
ATP5J2	9551	P56134	0.63
MRPL42	28977	Q9Y6G3	0.63
MRPL27	51264	Q9P0M9	0.63
MRPL49	740	Q13405	0.72
HNRNPU	3192	Q00839	0.72
OXA1L	5018	Q15070	0.72
MRPL23	6150	Q16540	0.72
MRPL12	6182	P52815	0.72
TLN1	7094	Q9Y490	0.72
TST	7263	Q16762	0.72
XRCC2	7516	O43543	0.72
SMC1A	8243	Q14683	0.72
KCNAB2	8514	Q13303	0.72
GTF3C3	9330	Q9Y5Q9	0.72
GDF15	9518	Q99988	0.72
MRPL33	9553	O75394	0.72
SYNCRIP	10492	O60506	0.72
TBC1D8	11138	O95759	0.72
MRPL3	11222	P09001	0.72
FASTKD2	22868	Q9NYY8	0.72
EXOSC7	23016	Q15024	0.72
FAM120A	23196	Q9NZB2	0.72
UBR2	23304	Q8IWV8	0.72
MRPL46	26589	Q9H2W6	0.72
TRUB2	26995	O95900	0.72
MRPL13	28998	Q9BYD1	0.72
MRPL18	29074	Q9H0U6	0.72
MRPL22	29093	Q9NWU5	0.72
MTERF3	51001	Q96E29	0.72
YARS2	51067	Q9Y2Z4	0.72
MRPL2	51069	Q5T653	0.72
MRPL51	51258	Q4U2R6	0.72
MRPL30	51263	Q8TCC3	0.72
MRPL35	51318	Q9NZE8	0.72
NGRN	51335	Q9NPE2	0.72
PCF11	51585	O94913	0.72
MRPL48	51642	Q96GC5	0.72
GAR1	54433	Q9NY12	0.72
MRPL16	54948	Q9NX20	0.72
MOCOS	55034	Q96EN8	0.72
MRPL20	55052	Q9BYC9	0.72
MRPS18A	55168	Q9NVS2	0.72
ZC3H15	55854	Q8WU90	0.72
RNF213	57674	Q63HN8	0.72
MRPS35	60488	P82673	0.72
MRPL17	63875	Q9NRX2	0.72
MRPL14	64928	Q6P1L8	0.72
MRPS6	64968	P82932	0.72
MRPL41	64975	Q8IXM3	0.72
MRPL34	64981	Q9BQ48	0.72
CORO7	79585	P57737	0.72
MRPL24	79590	Q96A35	0.72
THAP9	79725	Q9H5L6	0.72
WBSCR16	81554	Q96I51	0.72
MRPL43	84545	Q8N983	0.72
RTN4IP1	84816	Q8WWV3	0.72
MICALL1	85377	Q8N3F8	0.72
GADD45GIP1	90480	Q8TAE8	0.72
MRPL53	116540	Q96EL3	0.72
MRPL54	116541	Q6P161	0.72
MRPL52	122704	Q86TS9	0.72
MRPL10	124995	Q7Z7H8	0.72
MRPL55	128308	Q7Z7F7	0.72
MRPL21	219927	Q7Z2W9	0.72
REEP3	221035	Q6NUK4	0.72
RPUSD3	285367	Q6P087	0.72
ILF2	3608	Q12905	0.49
SLC25A3	5250	Q00325	0.49
FLOT1	10211	O75955	0.49
RIF1	55183	Q5UIP0	0.49
MDM2	4193	Q00987	0.63
NPM1	4869	P06748	0.63
RPL13	6137	P26373	0.63
CUL3	8452	Q13618	0.63
FOXB1	27023	Q99853	0.72
MRPL9	65005	Q9BYD2	0.72
MRPL1	65008	Q9BYD6	0.72
MRPL4	51073	Q9BYD3	0.73
ICT1	3396	Q14197	0.82
MRPL19	9801	P49406	0.82
MRPL28	10573	Q13084	0.82
MRPS30	10884	Q9NP92	0.82
MRPL15	29088	Q9P015	0.82
MRPL37	51253	Q9BZE1	0.82
MRPL39	54148	Q9NYK5	0.82
MRPL40	64976	Q9NQ50	0.82
MRPL38	64978	Q96DV4	0.82
MRPL32	64983	Q9BYC8	0.82
MRPL44	65080	Q9H9J2	0.82
MRPL45	84311	Q9BRJ2	0.82
MRPL47	57129	Q9HD33	0.83