Protein Description

Gene Symbol USP53
Entrez ID 54532
Uniprot ID Q70EK8
Description ubiquitin specific peptidase 53
Chromosomal Location chr4: 119,212,587-119,295,517
Ontology GO ID GO Term Definition Evidence

BP

GO:0007605

sensory perception of sound

The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.

IEA

BP

GO:0008150

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

ND

BP

GO:0016579

protein deubiquitination

The removal of one or more ubiquitin groups from a protein.

IEA

CC

GO:0005575

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

ND

MF

GO:0036459

thiol-dependent ubiquitinyl hydrolase activity

Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.

IEA

Domain ID Description

IPR001394

Peptidase C19, ubiquitin carboxyl-terminal hydrolase

IPR028889

Ubiquitin specific protease domain

No pathways found.

No diseases found.

Tissue Cell Type

colon

glandular cells

colon

peripheral nerve/ganglion

duodenum

glandular cells

epididymis

glandular cells

esophagus

squamous epithelial cells

kidney

cells in tubules

rectum

glandular cells

skeletal muscle

myocytes

small intestine

glandular cells

stomach

glandular cells

testis

cells in seminiferous ducts

tonsil

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

18765015

Qiao et al.

2008

Microarray evaluation of endometrial receptivity in Chinese women with polycystic ovary syndrome

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

GRB2

2885

P62993

0.63

IREB2

3658

P48200

0.63

YAE1D1

57002

Q9NRH1

0.72

ANXA2P2

304

A6NMY6

0.76

ARG1

383

P05089

0.76

AZGP1

563

P25311

0.76

BLMH

642

Q13867

0.76

CAT

847

P04040

0.76

CSTA

1475

P01040

0.76

DSG1

1828

Q02413

0.76

FLNC

2318

Q14315

0.76

HCFC1

3054

P51610

0.76

PPP2R1B

5519

P30154

0.76

PSMA6

5687

P60900

0.76

RPL26

6154

P61254

0.76

TGM3

7053

Q08188

0.76

RAD50

10111

Q92878

0.76

CASP14

23581

P31944

0.76

CPNE7

27132

Q9UBL6

0.76

KRT77

374454

Q7Z794

0.76

DAB1

1600

O75553

0.63

NECTIN2

5819

Q92692

0.63

DDB2

1643

Q92466

0.72

TRAF2

7186

Q12933

0.73