PCOSBase

Protein Description

Ontology	GO ID	GO Term	Definition	Evidence
BP	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.	IEA
BP	GO:0007420	brain development	The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).	ISS
CC	GO:0005886	plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.	IEA
CC	GO:0016021	integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	IEA
MF	GO:0005509	calcium ion binding	Interacting selectively and non-covalently with calcium ions (Ca2+).	IEA

Tissue	Cell Type
adrenal gland	glandular cells
appendix	glandular cells
bone marrow	hematopoietic cells
breast	glandular cells
breast	myoepithelial cells
caudate	neuronal cells
cerebellum	cells in molecular layer
cerebellum	Purkinje cells
cerebral cortex	neuronal cells
colon	glandular cells
colon	peripheral nerve/ganglion
duodenum	glandular cells
endometrium	glandular cells
epididymis	glandular cells
esophagus	squamous epithelial cells
fallopian tube	glandular cells
gallbladder	glandular cells
hippocampus	neuronal cells
lung	macrophages
lymph node	non-germinal center cells
nasopharynx	respiratory epithelial cells
ovary	follicle cells
pancreas	exocrine glandular cells
parathyroid gland	glandular cells
placenta	trophoblastic cells
prostate	glandular cells
rectum	glandular cells
salivary gland	glandular cells
seminal vesicle	glandular cells
skeletal muscle	myocytes
skin	fibroblasts
skin	epidermal cells
small intestine	glandular cells
soft tissue	fibroblasts
stomach	glandular cells
testis	Leydig cells
thyroid gland	glandular cells
tonsil	non-germinal center cells
tonsil	squamous epithelial cells
vagina	squamous epithelial cells

Pubmed ID	Author	Year	Title
15308691	Jansen et al.	2004	Abnormal Gene Expression Profiles in Human Ovaries from Polycystic Ovary Syndrome Patients
23824412	Piltonen et al.	2013	Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential

Gene Symbol	Entrez ID	Uniprot ID	Score
DAB1	1600	O75553	0.67
BRK1	55845	Q8WUW1	0.56
ATG5	9474	Q9H1Y0	0.63