Protein Description

Gene Symbol PHAX
Entrez ID 51808
Uniprot ID Q9H814
Description phosphorylated adaptor for RNA export
Chromosomal Location chr5: 126,600,268-126,627,252
Ontology GO ID GO Term Definition Evidence

BP

GO:0006408

snRNA export from nucleus

The directed movement of snRNA from the nucleus to the cytoplasm.

TAS

BP

GO:0015031

protein transport

The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

IEA

BP

GO:0042795

snRNA transcription from RNA polymerase II promoter

The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.

TAS

BP

GO:0051168

nuclear export

The directed movement of substances out of the nucleus.

TAS

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IBA|IDA

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

IDA|TAS

CC

GO:0005813

centrosome

A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.

IDA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

TAS

CC

GO:0015030

Cajal body

A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.

IEA

CC

GO:0043025

neuronal cell body

The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.

IEA

CC

GO:0043231

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

IDA

MF

GO:0003723

RNA binding

Interacting selectively and non-covalently with an RNA molecule or a portion thereof.

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0015643

toxic substance binding

Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems.

IEA

Domain ID Description

IPR019385

Phosphorylated adapter RNA export protein, RNA-binding domain

Pathway ID Pathway Term Pathway Source

hsa03013

RNA transport

KEGG

No diseases found.

Tissue Cell Type

lymph node

non-germinal center cells

parathyroid gland

glandular cells

placenta

decidual cells

tonsil

non-germinal center cells

tonsil

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

FAM20B

9917

O75063

0.63

CALD1

800

Q05682

0.63

SNORD13P1

6076

N/A

0.63

RPL10

6134

P27635

0.63

HSP90B1

7184

P14625

0.63

SNORD118

727676

N/A

0.63

KPNA1

3836

P52294

0.72

NCBP1

4686

Q09161

0.72

SSRP1

6749

Q08945

0.72

TNFRSF1A

7132

P19438

0.72

SPATS2

65244

Q86XZ4

0.72

REEP4

80346

Q9H6H4

0.72

HIST2H3A; HIST2H3C; HIST2H3D

126961

Q71DI3

0.72

XPO1

7514

O14980

0.77

EIF4B

1975

P23588

0.49

EWSR1

2130

Q01844

0.49

HUWE1

10075

Q7Z6Z7

0.49

NUCKS1

64710

Q9H1E3

0.49

FBL

2091

P22087

0.63

GRB7

2886

Q14451

0.63

JUN

3725

P05412

0.63

PDPK1

5170

O15530

0.63

RAD23A

5886

P54725

0.63

RPS6KA1

6195

Q15418

0.63

SNRPA1

6627

P09661

0.63

STK3

6788

Q13188

0.63

TULP3

7289

O75386

0.63

VAV1

7409

P15498

0.63

CUL3

8452

Q13618

0.63

MKNK1

8569

Q9BUB5

0.63

TNFSF11

8600

O14788

0.63

CIAO1

9391

O76071

0.63

KIAA0101

9768

Q15004

0.63

GADD45G

10912

O95257

0.63

ZWINT

11130

O95229

0.63

PAXIP1

22976

Q6ZW49

0.63

ZNF346

23567

Q9UL40

0.63

TRA2A

29896

Q13595

0.63

CAND1

55832

Q86VP6

0.63

NSFL1C

55968

Q9UNZ2

0.63

ASPSCR1

79058

Q9BZE9

0.63

LIN28A

79727

Q9H9Z2

0.63

NIFK

84365

Q9BYG3

0.63

UBXN2A

165324

P68543

0.63

LIN28B

389421

Q6ZN17

0.63

NCBP2

22916

P52298

0.72

SUMO2

6613

P61956

0.73