Gene Symbol | PHAX |
Entrez ID | 51808 |
Uniprot ID | Q9H814 |
Description | phosphorylated adaptor for RNA export |
Chromosomal Location | chr5: 126,600,268-126,627,252 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006408 |
snRNA export from nucleus |
The directed movement of snRNA from the nucleus to the cytoplasm. |
TAS |
BP |
GO:0015031 |
protein transport |
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
IEA |
BP |
GO:0042795 |
snRNA transcription from RNA polymerase II promoter |
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter. |
TAS |
BP |
GO:0051168 |
nuclear export |
The directed movement of substances out of the nucleus. |
TAS |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IBA|IDA |
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA|TAS |
CC |
GO:0005813 |
centrosome |
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. |
IDA |
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
TAS |
CC |
GO:0015030 |
Cajal body |
A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. |
IEA |
CC |
GO:0043025 |
neuronal cell body |
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. |
IEA |
CC |
GO:0043231 |
intracellular membrane-bounded organelle |
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
IDA |
MF |
GO:0003723 |
RNA binding |
Interacting selectively and non-covalently with an RNA molecule or a portion thereof. |
IEA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0015643 |
toxic substance binding |
Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems. |
IEA |
Domain ID | Description |
---|---|
IPR019385 |
Phosphorylated adapter RNA export protein, RNA-binding domain |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa03013 |
RNA transport |
KEGG |
Tissue | Cell Type |
---|---|
lymph node |
non-germinal center cells |
parathyroid gland |
glandular cells |
placenta |
decidual cells |
tonsil |
non-germinal center cells |
tonsil |
squamous epithelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
FAM20B |
9917 |
O75063 |
0.63 |
CALD1 |
800 |
Q05682 |
0.63 |
SNORD13P1 |
6076 |
N/A |
0.63 |
RPL10 |
6134 |
P27635 |
0.63 |
HSP90B1 |
7184 |
P14625 |
0.63 |
SNORD118 |
727676 |
N/A |
0.63 |
KPNA1 |
3836 |
P52294 |
0.72 |
NCBP1 |
4686 |
Q09161 |
0.72 |
SSRP1 |
6749 |
Q08945 |
0.72 |
TNFRSF1A |
7132 |
P19438 |
0.72 |
SPATS2 |
65244 |
Q86XZ4 |
0.72 |
REEP4 |
80346 |
Q9H6H4 |
0.72 |
HIST2H3A; HIST2H3C; HIST2H3D |
126961 |
Q71DI3 |
0.72 |
XPO1 |
7514 |
O14980 |
0.77 |
EIF4B |
1975 |
P23588 |
0.49 |
EWSR1 |
2130 |
Q01844 |
0.49 |
HUWE1 |
10075 |
Q7Z6Z7 |
0.49 |
NUCKS1 |
64710 |
Q9H1E3 |
0.49 |
FBL |
2091 |
P22087 |
0.63 |
GRB7 |
2886 |
Q14451 |
0.63 |
JUN |
3725 |
P05412 |
0.63 |
PDPK1 |
5170 |
O15530 |
0.63 |
RAD23A |
5886 |
P54725 |
0.63 |
RPS6KA1 |
6195 |
Q15418 |
0.63 |
SNRPA1 |
6627 |
P09661 |
0.63 |
STK3 |
6788 |
Q13188 |
0.63 |
TULP3 |
7289 |
O75386 |
0.63 |
VAV1 |
7409 |
P15498 |
0.63 |
CUL3 |
8452 |
Q13618 |
0.63 |
MKNK1 |
8569 |
Q9BUB5 |
0.63 |
TNFSF11 |
8600 |
O14788 |
0.63 |
CIAO1 |
9391 |
O76071 |
0.63 |
KIAA0101 |
9768 |
Q15004 |
0.63 |
GADD45G |
10912 |
O95257 |
0.63 |
ZWINT |
11130 |
O95229 |
0.63 |
PAXIP1 |
22976 |
Q6ZW49 |
0.63 |
ZNF346 |
23567 |
Q9UL40 |
0.63 |
TRA2A |
29896 |
Q13595 |
0.63 |
CAND1 |
55832 |
Q86VP6 |
0.63 |
NSFL1C |
55968 |
Q9UNZ2 |
0.63 |
ASPSCR1 |
79058 |
Q9BZE9 |
0.63 |
LIN28A |
79727 |
Q9H9Z2 |
0.63 |
NIFK |
84365 |
Q9BYG3 |
0.63 |
UBXN2A |
165324 |
P68543 |
0.63 |
LIN28B |
389421 |
Q6ZN17 |
0.63 |
NCBP2 |
22916 |
P52298 |
0.72 |
SUMO2 |
6613 |
P61956 |
0.73 |