PCOSBase

Protein Description

Ontology	GO ID	GO Term	Definition	Evidence
BP	GO:0006400	tRNA modification	The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.	TAS
BP	GO:0030488	tRNA methylation	The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.	IEA
CC	GO:0005654	nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.	TAS
CC	GO:0031515	tRNA (m1A) methyltransferase complex	A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer.	IEA
MF	GO:0044822	poly(A) RNA binding	Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.	IDA

Domain ID	Description
IPR017423	tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6

Pubmed ID	Author	Year	Title
22951915	Haozi et al.	2012	Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol	Entrez ID	Uniprot ID	Score
ATP6V1B2	526	P21281	0.49
DDX5	1655	P17844	0.49
EIF2B1	1967	Q14232	0.49
SNU13	4809	P55769	0.49
RDX	5962	P35241	0.49
TTC4	7268	O95801	0.49
STK24	8428	Q9Y6E0	0.49
UTP14A	10813	Q9BVJ6	0.49
SNW1	22938	Q13573	0.49
DNAJC17	55192	Q9NVM6	0.49
VPS35	55737	Q96QK1	0.49
PUS1	80324	Q9Y606	0.49
TLN2	83660	Q9Y4G6	0.49
FOXJ1	2302	Q92949	0.63
HHEX	3087	Q03014	0.63
OGFR	11054	Q9NZT2	0.63
SHTN1	57698	A0MZ66	0.63
EPRS	2058	P07814	0.49
MARS	4141	P56192	0.49
PTK2	5747	Q05397	0.49
QARS	5859	P47897	0.49
SSB	6741	P05455	0.49
NAPA	8775	P54920	0.49
HNRNPR	10236	O43390	0.49
SKIV2L2	23517	P42285	0.49
NMD3	51068	Q96D46	0.49
DUS3L	56931	Q96G46	0.49
DDI2	84301	Q5TDH0	0.49
JUN	3725	P05412	0.63
NTRK1	4914	P04629	0.63
PPARD	5467	Q03181	0.63
CUL3	8452	Q13618	0.63
PSME3	10197	P61289	0.63
CAND1	55832	Q86VP6	0.63
USE1	55850	Q9NZ43	0.63
CBWD1	55871	Q9BRT8	0.63
GRIA2	2891	P42262	0.72
RAPGEF2	9693	Q9Y4G8	0.72
CKAP5	9793	Q14008	0.72
NCSTN	23385	Q92542	0.72
DCP1A	55802	Q9NPI6	0.72
NETO2	81831	Q8NC67	0.72
USP43	124739	Q70EL4	0.72
TRMT61A	115708	Q96FX7	0.93