| Gene Symbol | TRMT6 |
| Entrez ID | 51605 |
| Uniprot ID | Q9UJA5 |
| Description | tRNA methyltransferase 6 |
| Chromosomal Location | chr20: 5,937,235-5,950,558 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006400 |
tRNA modification |
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. |
TAS |
|
BP |
GO:0030488 |
tRNA methylation |
The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule. |
IEA |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
TAS |
|
CC |
GO:0031515 |
tRNA (m1A) methyltransferase complex |
A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer. |
IEA |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR017423 |
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
cerebellum |
Purkinje cells |
|
esophagus |
squamous epithelial cells |
|
seminal vesicle |
glandular cells |
|
skin |
epidermal cells |
|
testis |
cells in seminiferous ducts |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
ATP6V1B2 |
526 |
P21281 |
0.49 |
|
DDX5 |
1655 |
P17844 |
0.49 |
|
EIF2B1 |
1967 |
Q14232 |
0.49 |
|
SNU13 |
4809 |
P55769 |
0.49 |
|
RDX |
5962 |
P35241 |
0.49 |
|
TTC4 |
7268 |
O95801 |
0.49 |
|
STK24 |
8428 |
Q9Y6E0 |
0.49 |
|
UTP14A |
10813 |
Q9BVJ6 |
0.49 |
|
SNW1 |
22938 |
Q13573 |
0.49 |
|
DNAJC17 |
55192 |
Q9NVM6 |
0.49 |
|
VPS35 |
55737 |
Q96QK1 |
0.49 |
|
PUS1 |
80324 |
Q9Y606 |
0.49 |
|
TLN2 |
83660 |
Q9Y4G6 |
0.49 |
|
FOXJ1 |
2302 |
Q92949 |
0.63 |
|
HHEX |
3087 |
Q03014 |
0.63 |
|
OGFR |
11054 |
Q9NZT2 |
0.63 |
|
SHTN1 |
57698 |
A0MZ66 |
0.63 |
|
EPRS |
2058 |
P07814 |
0.49 |
|
MARS |
4141 |
P56192 |
0.49 |
|
PTK2 |
5747 |
Q05397 |
0.49 |
|
QARS |
5859 |
P47897 |
0.49 |
|
SSB |
6741 |
P05455 |
0.49 |
|
NAPA |
8775 |
P54920 |
0.49 |
|
HNRNPR |
10236 |
O43390 |
0.49 |
|
SKIV2L2 |
23517 |
P42285 |
0.49 |
|
NMD3 |
51068 |
Q96D46 |
0.49 |
|
DUS3L |
56931 |
Q96G46 |
0.49 |
|
DDI2 |
84301 |
Q5TDH0 |
0.49 |
|
JUN |
3725 |
P05412 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
PPARD |
5467 |
Q03181 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
PSME3 |
10197 |
P61289 |
0.63 |
|
CAND1 |
55832 |
Q86VP6 |
0.63 |
|
USE1 |
55850 |
Q9NZ43 |
0.63 |
|
CBWD1 |
55871 |
Q9BRT8 |
0.63 |
|
GRIA2 |
2891 |
P42262 |
0.72 |
|
RAPGEF2 |
9693 |
Q9Y4G8 |
0.72 |
|
CKAP5 |
9793 |
Q14008 |
0.72 |
|
NCSTN |
23385 |
Q92542 |
0.72 |
|
DCP1A |
55802 |
Q9NPI6 |
0.72 |
|
NETO2 |
81831 |
Q8NC67 |
0.72 |
|
USP43 |
124739 |
Q70EL4 |
0.72 |
|
TRMT61A |
115708 |
Q96FX7 |
0.93 |