Protein Description

Gene Symbol GPR89B
Entrez ID 51463
Uniprot ID P0CG08
Description G protein-coupled receptor 89B
Chromosomal Location chr1: 147,928,393-147,993,521
Ontology GO ID GO Term Definition Evidence

BP

GO:0006811

ion transport

The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

IEA

BP

GO:0007165

signal transduction

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

IEA

BP

GO:0015031

protein transport

The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

IEA

BP

GO:0034765

regulation of ion transmembrane transport

Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.

IEA

BP

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB signaling

Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.

IMP

BP

GO:0051452

intracellular pH reduction

Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion.

IDA

BP

GO:1903959

regulation of anion transmembrane transport

Any process that modulates the frequency, rate or extent of anion transmembrane transport.

IEA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

IEA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

CC

GO:0030660

Golgi-associated vesicle membrane

The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.

IDA

CC

GO:0032580

Golgi cisterna membrane

The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.

IDA

MF

GO:0004871

signal transducer activity

Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.

IMP

MF

GO:0005244

voltage-gated ion channel activity

Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

IEA

MF

GO:0008308

voltage-gated anion channel activity

Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

IDA

Domain ID Description

IPR015672

The Golgi pH regulator/GPCR-type G protein

IPR022535

Golgi pH regulator, conserved domain

IPR025969

Abscisic acid G-protein coupled receptor-like domain

No pathways found.

No diseases found.

No tissues found.

No databases found.

Pubmed ID Author Year Title

15598877

Wood et al.

2005

Valproate-induced alterations in human theca cell gene expression: clues to the association between valproate use and metabolic side effects

No partners found.