| Gene Symbol | CHST15 |
| Entrez ID | 51363 |
| Uniprot ID | Q7LFX5 |
| Description | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| Chromosomal Location | chr10: 124,007,666-124,093,607 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0019319 | hexose biosynthetic process |
The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule. | IDA |
BP | GO:0030206 | chondroitin sulfate biosynthetic process |
The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. | TAS |
CC | GO:0000139 | Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. | TAS |
CC | GO:0016021 | integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. | NAS |
MF | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding |
Interacting selectively and non-covalently with 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems. | IDA |
MF | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity |
Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate. | IDA|TAS |
| Domain ID | Description |
|---|---|
IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
hsa00532 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | KEGG |
| Tissue | Cell Type |
|---|---|
duodenum | glandular cells |
heart muscle | myocytes |
kidney | cells in tubules |
ovary | follicle cells |
stomach | glandular cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22617121 | Ouandaogo et al. | 2012 | Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22904171 | Kaur et al. | 2012 | Differential Gene Expression in Granulosa Cells from Polycystic Ovary Syndrome Patients with and without Insulin Resistance: Identification of Susceptibility Gene Sets through Network Analysis |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
LYN | 4067 | P07948 | 0.52 |
RRAGD | 58528 | Q9NQL2 | 0.52 |
SLC43A3 | 29015 | Q8NBI5 | 0.63 |
CANX | 821 | P27824 | 0.72 |
CCNB1 | 891 | P14635 | 0.72 |
EIF5A | 1984 | P63241 | 0.72 |
HIVEP1 | 3096 | P15822 | 0.72 |
LPGAT1 | 9926 | Q92604 | 0.72 |
CEPT1 | 10390 | Q9Y6K0 | 0.72 |
FARS2 | 10667 | O95363 | 0.72 |
CASC3 | 22794 | O15234 | 0.72 |
ERC1 | 23085 | Q8IUD2 | 0.72 |
KLHDC2 | 23588 | Q9Y2U9 | 0.72 |
RABL6 | 55684 | Q3YEC7 | 0.72 |
PLEKHG1 | 57480 | Q9ULL1 | 0.72 |
SLC25A19 | 60386 | Q9HC21 | 0.72 |
SLC35E1 | 79939 | Q96K37 | 0.72 |
ILKAP | 80895 | Q9H0C8 | 0.72 |
PHF5A | 84844 | Q7RTV0 | 0.72 |
NDUFAF2 | 91942 | Q8N183 | 0.72 |
TJAP1 | 93643 | Q5JTD0 | 0.72 |
HCK | 3055 | P08631 | 0.73 |