Protein Description

Gene Symbol CHST15
Entrez ID 51363
Uniprot ID Q7LFX5
Description carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
Chromosomal Location chr10: 124,007,666-124,093,607
Ontology GO ID GO Term Definition Evidence

BP

GO:0019319

hexose biosynthetic process

The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.

IDA

BP

GO:0030206

chondroitin sulfate biosynthetic process

The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.

TAS

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

TAS

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

NAS

MF

GO:0050656

3'-phosphoadenosine 5'-phosphosulfate binding

Interacting selectively and non-covalently with 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.

IDA

MF

GO:0050659

N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity

Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.

IDA|TAS

Domain ID Description

IPR027417

P-loop containing nucleoside triphosphate hydrolase

Pathway ID Pathway Term Pathway Source

hsa00532

Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

KEGG

No diseases found.

Tissue Cell Type

duodenum

glandular cells

heart muscle

myocytes

kidney

cells in tubules

ovary

follicle cells

stomach

glandular cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

22904171

Kaur et al.

2012

Differential Gene Expression in Granulosa Cells from Polycystic Ovary Syndrome Patients with and without Insulin Resistance: Identification of Susceptibility Gene Sets through Network Analysis

Gene Symbol Entrez ID Uniprot ID Score

LYN

4067

P07948

0.52

RRAGD

58528

Q9NQL2

0.52

SLC43A3

29015

Q8NBI5

0.63

CANX

821

P27824

0.72

CCNB1

891

P14635

0.72

EIF5A

1984

P63241

0.72

HIVEP1

3096

P15822

0.72

LPGAT1

9926

Q92604

0.72

CEPT1

10390

Q9Y6K0

0.72

FARS2

10667

O95363

0.72

CASC3

22794

O15234

0.72

ERC1

23085

Q8IUD2

0.72

KLHDC2

23588

Q9Y2U9

0.72

RABL6

55684

Q3YEC7

0.72

PLEKHG1

57480

Q9ULL1

0.72

SLC25A19

60386

Q9HC21

0.72

SLC35E1

79939

Q96K37

0.72

ILKAP

80895

Q9H0C8

0.72

PHF5A

84844

Q7RTV0

0.72

NDUFAF2

91942

Q8N183

0.72

TJAP1

93643

Q5JTD0

0.72

HCK

3055

P08631

0.73