Gene Symbol | KLF3 |
Entrez ID | 51274 |
Uniprot ID | P57682 |
Description | Kruppel-like factor 3 (basic) |
Chromosomal Location | chr4: 38,664,196-38,701,042 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006351 |
transcription, DNA-templated |
The cellular synthesis of RNA on a template of DNA. |
IEA |
BP |
GO:0006355 |
regulation of transcription, DNA-templated |
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
IEA |
BP |
GO:0007275 |
multicellular organism development |
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). |
TAS |
BP |
GO:1901653 |
cellular response to peptide |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. |
IEA |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IEA |
MF |
GO:0003677 |
DNA binding |
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
IEA |
MF |
GO:0003700 |
transcription factor activity, sequence-specific DNA binding |
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. |
NAS |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0046872 |
metal ion binding |
Interacting selectively and non-covalently with any metal ion. |
IEA |
Domain ID | Description |
---|---|
IPR013083 |
Zinc finger, RING/FYVE/PHD-type |
IPR013087 |
Zinc finger C2H2-type |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa05202 |
Transcriptional misregulation in cancer |
KEGG |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
appendix |
glandular cells |
bone marrow |
hematopoietic cells |
breast |
glandular cells |
bronchus |
respiratory epithelial cells |
caudate |
glial cells |
cerebellum |
Purkinje cells |
cerebral cortex |
endothelial cells |
cerebral cortex |
glial cells |
cerebral cortex |
neuronal cells |
cervix, uterine |
glandular cells |
cervix, uterine |
squamous epithelial cells |
colon |
glandular cells |
colon |
peripheral nerve/ganglion |
duodenum |
glandular cells |
epididymis |
glandular cells |
esophagus |
squamous epithelial cells |
fallopian tube |
glandular cells |
gallbladder |
glandular cells |
heart muscle |
myocytes |
hippocampus |
glial cells |
hippocampus |
neuronal cells |
kidney |
cells in glomeruli |
kidney |
cells in tubules |
lymph node |
non-germinal center cells |
nasopharynx |
respiratory epithelial cells |
oral mucosa |
squamous epithelial cells |
parathyroid gland |
glandular cells |
prostate |
glandular cells |
rectum |
glandular cells |
salivary gland |
glandular cells |
seminal vesicle |
glandular cells |
skeletal muscle |
myocytes |
skin |
keratinocytes |
skin |
Langerhans |
skin |
melanocytes |
skin |
epidermal cells |
small intestine |
glandular cells |
spleen |
cells in red pulp |
stomach |
glandular cells |
testis |
cells in seminiferous ducts |
testis |
Leydig cells |
thyroid gland |
glandular cells |
tonsil |
squamous epithelial cells |
urinary bladder |
urothelial cells |
vagina |
squamous epithelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
LHX8 |
431707 |
Q68G74 |
0.63 |
KDM1A |
23028 |
O60341 |
0.72 |
SUV39H2 |
79723 |
Q9H5I1 |
0.72 |
CTBP2 |
1488 |
P56545 |
0.89 |
CTBP1 |
1487 |
Q13363 |
0.63 |
DVL3 |
1857 |
Q92997 |
0.63 |
SUMO2 |
6613 |
P61956 |
0.63 |
TRAF2 |
7186 |
Q12933 |
0.63 |
EHMT2 |
10919 |
Q96KQ7 |
0.63 |
FHL3 |
2275 |
Q13643 |
0.89 |