| Gene Symbol | MRPL4 |
| Entrez ID | 51073 |
| Uniprot ID | Q9BYD3 |
| Description | mitochondrial ribosomal protein L4 |
| Chromosomal Location | chr19: 10,251,901-10,260,045 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006412 |
translation |
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
IBA |
|
BP |
GO:0070125 |
mitochondrial translational elongation |
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion. |
TAS |
|
BP |
GO:0070126 |
mitochondrial translational termination |
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa). |
TAS |
|
CC |
GO:0005743 |
mitochondrial inner membrane |
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
TAS |
|
CC |
GO:0022626 |
cytosolic ribosome |
A ribosome located in the cytosol. |
IBA |
|
MF |
GO:0003723 |
RNA binding |
Interacting selectively and non-covalently with an RNA molecule or a portion thereof. |
IBA |
|
MF |
GO:0003735 |
structural constituent of ribosome |
The action of a molecule that contributes to the structural integrity of the ribosome. |
IBA |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR002136 |
Ribosomal protein L4/L1e |
|
IPR013005 |
50S ribosomal protein uL4 |
|
IPR023574 |
Ribosomal protein L4 domain |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa03010 |
Ribosome |
KEGG |
| Tissue | Cell Type |
|---|---|
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
bone marrow |
hematopoietic cells |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
cervix, uterine |
glandular cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
kidney |
cells in tubules |
|
lymph node |
germinal center cells |
|
pancreas |
islets of Langerhans |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
smooth muscle |
smooth muscle cells |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
RPL17 |
6139 |
P18621 |
0.49 |
|
RPS18 |
6222 |
P62269 |
0.49 |
|
RPL8 |
6132 |
P62917 |
0.56 |
|
RPS2 |
6187 |
P15880 |
0.56 |
|
MRPL49 |
740 |
Q13405 |
0.63 |
|
CSNK1E |
1454 |
P49674 |
0.63 |
|
GLS |
2744 |
O94925 |
0.63 |
|
HNRNPA1 |
3178 |
P09651 |
0.63 |
|
HSPD1 |
3329 |
P10809 |
0.63 |
|
MKLN1 |
4289 |
Q9UL63 |
0.63 |
|
NEFL |
4747 |
P07196 |
0.63 |
|
POLG |
5428 |
P54098 |
0.63 |
|
GTPBP6 |
8225 |
O43824 |
0.63 |
|
MRPL33 |
9553 |
O75394 |
0.63 |
|
TATDN2 |
9797 |
Q93075 |
0.63 |
|
MRPL19 |
9801 |
P49406 |
0.63 |
|
RANBP9 |
10048 |
Q96S59 |
0.63 |
|
MAEA |
10296 |
Q7L5Y9 |
0.63 |
|
MRPS30 |
10884 |
Q9NP92 |
0.63 |
|
FASTKD2 |
22868 |
Q9NYY8 |
0.63 |
|
TCF25 |
22980 |
Q9BQ70 |
0.63 |
|
ZSWIM8 |
23053 |
A7E2V4 |
0.63 |
|
ARMC8 |
25852 |
Q8IUR7 |
0.63 |
|
PTCD1 |
26024 |
O75127 |
0.63 |
|
TRUB2 |
26995 |
O95900 |
0.63 |
|
MCAT |
27349 |
Q8IVS2 |
0.63 |
|
HTRA2 |
27429 |
O43464 |
0.63 |
|
MRPL42 |
28977 |
Q9Y6G3 |
0.63 |
|
MRPL22 |
29093 |
Q9NWU5 |
0.63 |
|
MTERF3 |
51001 |
Q96E29 |
0.63 |
|
YARS2 |
51067 |
Q9Y2Z4 |
0.63 |
|
MRPL37 |
51253 |
Q9BZE1 |
0.63 |
|
MRPL30 |
51263 |
Q8TCC3 |
0.63 |
|
MRPL27 |
51264 |
Q9P0M9 |
0.63 |
|
MRPL35 |
51318 |
Q9NZE8 |
0.63 |
|
NGRN |
51335 |
Q9NPE2 |
0.63 |
|
UBR5 |
51366 |
O95071 |
0.63 |
|
CINP |
51550 |
Q9BW66 |
0.63 |
|
MRPL48 |
51642 |
Q96GC5 |
0.63 |
|
YPEL5 |
51646 |
P62699 |
0.63 |
|
MRPL39 |
54148 |
Q9NYK5 |
0.63 |
|
MRPL16 |
54948 |
Q9NX20 |
0.63 |
|
GID8 |
54994 |
Q9NWU2 |
0.63 |
|
PDPR |
55066 |
Q8NCN5 |
0.63 |
|
MRPS18A |
55168 |
Q9NVS2 |
0.63 |
|
MRM3 |
55178 |
Q9HC36 |
0.63 |
|
DDX28 |
55794 |
Q9NUL7 |
0.63 |
|
DDX24 |
57062 |
Q9GZR7 |
0.63 |
|
MRPL47 |
57129 |
Q9HD33 |
0.63 |
|
AARS2 |
57505 |
Q5JTZ9 |
0.63 |
|
RANBP10 |
57610 |
Q6VN20 |
0.63 |
|
SAV1 |
60485 |
Q9H4B6 |
0.63 |
|
RMND5B |
64777 |
Q96G75 |
0.63 |
|
RMND5A |
64795 |
Q9H871 |
0.63 |
|
MRPL41 |
64975 |
Q8IXM3 |
0.63 |
|
MRPL40 |
64976 |
Q9NQ50 |
0.63 |
|
MRPL34 |
64981 |
Q9BQ48 |
0.63 |
|
MRPL32 |
64983 |
Q9BYC8 |
0.63 |
|
MRPL44 |
65080 |
Q9H9J2 |
0.63 |
|
MRPL57 |
78988 |
Q9BQC6 |
0.63 |
|
GID4 |
79018 |
Q8IVV7 |
0.63 |
|
SPATA5L1 |
79029 |
Q9BVQ7 |
0.63 |
|
WDR26 |
80232 |
Q9H7D7 |
0.63 |
|
MRPL45 |
84311 |
Q9BRJ2 |
0.63 |
|
RPUSD4 |
84881 |
Q96CM3 |
0.63 |
|
GADD45GIP1 |
90480 |
Q8TAE8 |
0.63 |
|
MARS2 |
92935 |
Q96GW9 |
0.63 |
|
MALSU1 |
115416 |
Q96EH3 |
0.63 |
|
ZMYND19 |
116225 |
Q96E35 |
0.63 |
|
MRPL53 |
116540 |
Q96EL3 |
0.63 |
|
MRPL52 |
122704 |
Q86TS9 |
0.63 |
|
MSI2 |
124540 |
Q96DH6 |
0.63 |
|
MRPL10 |
124995 |
Q7Z7H8 |
0.63 |
|
MRPL55 |
128308 |
Q7Z7F7 |
0.63 |
|
MRPL21 |
219927 |
Q7Z2W9 |
0.63 |
|
RPUSD3 |
285367 |
Q6P087 |
0.63 |
|
FAM83H |
286077 |
Q6ZRV2 |
0.63 |
|
CSNK2A1 |
1457 |
P68400 |
0.70 |
|
MRPL13 |
28998 |
Q9BYD1 |
0.70 |
|
MRPL17 |
63875 |
Q9NRX2 |
0.70 |
|
MRPL11 |
65003 |
Q9Y3B7 |
0.70 |
|
MRPL18 |
29074 |
Q9H0U6 |
0.73 |
|
MRPL51 |
51258 |
Q4U2R6 |
0.73 |
|
MRPL50 |
54534 |
Q8N5N7 |
0.73 |
|
MRPL20 |
55052 |
Q9BYC9 |
0.73 |
|
MRPL14 |
64928 |
Q6P1L8 |
0.73 |
|
MRPL38 |
64978 |
Q96DV4 |
0.73 |
|
MRPL9 |
65005 |
Q9BYD2 |
0.73 |
|
MRPL24 |
79590 |
Q96A35 |
0.73 |
|
MRPL15 |
29088 |
Q9P015 |
0.74 |
|
MRPL23 |
6150 |
Q16540 |
0.79 |
|
MRPL46 |
26589 |
Q9H2W6 |
0.79 |
|
CYC1 |
1537 |
P08574 |
0.49 |
|
CD55 |
1604 |
P08174 |
0.49 |
|
ILF3 |
3609 |
Q12906 |
0.49 |
|
TUFM |
7284 |
P49411 |
0.49 |
|
HNRNPR |
10236 |
O43390 |
0.49 |
|
TRIM23 |
373 |
P36406 |
0.63 |
|
C1QBP |
708 |
Q07021 |
0.63 |
|
CLK2 |
1196 |
P49760 |
0.63 |
|
EIF2B1 |
1967 |
Q14232 |
0.63 |
|
GRSF1 |
2926 |
Q12849 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
PCNA |
5111 |
P12004 |
0.63 |
|
SUMO3 |
6612 |
P55854 |
0.63 |
|
SOX2 |
6657 |
P48431 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
BTRC |
8945 |
Q9Y297 |
0.63 |
|
MRPL28 |
10573 |
Q13084 |
0.63 |
|
XRN2 |
22803 |
Q9H0D6 |
0.63 |
|
FBXW11 |
23291 |
Q9UKB1 |
0.63 |
|
L1TD1 |
54596 |
Q5T7N2 |
0.63 |
|
CAND1 |
55832 |
Q86VP6 |
0.63 |
|
ACKR3 |
57007 |
P25106 |
0.63 |
|
MRPL43 |
84545 |
Q8N983 |
0.63 |
|
EXOSC6 |
118460 |
Q5RKV6 |
0.63 |
|
MRPL1 |
65008 |
Q9BYD6 |
0.73 |
|
KRTAP4-12 |
83755 |
Q9BQ66 |
0.73 |
|
MRPL2 |
51069 |
Q5T653 |
0.79 |
|
MRPL3 |
11222 |
P09001 |
0.80 |
|
ICT1 |
3396 |
Q14197 |
0.83 |