PCOSBase

Protein Description

Gene Symbol	GOLT1B
Entrez ID	51026
Uniprot ID	Q9Y3E0
Description	golgi transport 1B
Chromosomal Location	chr12: 21,501,781-21,518,408

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Ontology	GO ID	GO Term	Definition	Evidence
BP	GO:0007165	signal transduction	The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.	IEA
BP	GO:0015031	protein transport	The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	IEA
BP	GO:0016192	vesicle-mediated transport	A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.	IEA
BP	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.	IMP
CC	GO:0000139	Golgi membrane	The lipid bilayer surrounding any of the compartments of the Golgi apparatus.	IEA
CC	GO:0005783	endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).	IDA
CC	GO:0016020	membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.	IDA
CC	GO:0016021	integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	IEA
MF	GO:0004871	signal transducer activity	Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.	IMP

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Domain ID	Description
IPR007305	Vesicle transport protein, Got1/SFT2-like

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No pathways found.

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No diseases found.

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Tissue	Cell Type
breast	glandular cells
kidney	cells in glomeruli
kidney	cells in tubules
liver	hepatocytes
testis	Leydig cells

Database Name
GWASdb

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Pubmed ID	Author	Year	Title
22951915	Haozi et al.	2012	Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

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Gene Symbol	Entrez ID	Uniprot ID	Score
STOM	2040	P27105	0.63
EXTL2	2135	Q9UBQ6	0.63
PDIA3	2923	P30101	0.63
MAP3K4	4216	Q9Y6R4	0.63
NDUFS8	4728	O00217	0.63
CHPF2	54480	Q9P2E5	0.63
TMUB1	83590	Q9BVT8	0.63
MYADM	91663	Q96S97	0.63
TMEM199	147007	Q8N511	0.63
SFT2D2	375035	O95562	0.63
ANXA1	301	P04083	0.72
ATP1A1	476	P05023	0.72
ATP2A2	488	P16615	0.72
ATP5A1	498	P25705	0.72
ATP5B	506	P06576	0.72
ATP5J	522	P18859	0.72
ATP6V1A	523	P38606	0.72
ATP6V1B2	526	P21281	0.72
ATP6V1E1	529	P36543	0.72
ATP6V0A1	535	Q93050	0.72
ATP6AP1	537	Q15904	0.72
ATP5O	539	P48047	0.72
C1QBP	708	Q07021	0.72
CALU	813	O43852	0.72
CAV1	857	Q03135	0.72
CD59	966	P13987	0.72
CD97	976	P48960	0.72
CDC42	998	P60953	0.72
CLCN7	1186	P51798	0.72
COX4I1	1327	P13073	0.72
CPM	1368	P14384	0.72
CYC1	1537	P08574	0.72
DSG2	1829	Q14126	0.72
ETFB	2109	P38117	0.72
FLOT2	2319	Q14254	0.72
GOLGA2	2801	Q08379	0.72
JUP	3728	P14923	0.72
KTN1	3895	Q86UP2	0.72
LBR	3930	Q14739	0.72
LGALS1	3956	P09382	0.72
LIFR	3977	P42702	0.72
RAB8A	4218	P61006	0.72
MGST3	4259	O14880	0.72
NDUFA2	4695	O43678	0.72
NDUFA5	4698	Q16718	0.72
NDUFA6	4700	P56556	0.72
NDUFA7	4701	O95182	0.72
NDUFA8	4702	P51970	0.72
NDUFA9	4704	Q16795	0.72
NDUFA10	4705	O95299	0.72
NDUFB1	4707	O75438	0.72
NDUFB4	4710	O95168	0.72
NDUFB7	4713	P17568	0.72
NDUFB8	4714	O95169	0.72
NDUFS1	4719	P28331	0.72
NDUFS2	4720	O75306	0.72
NDUFS3	4722	O75489	0.72
NDUFV1	4723	P49821	0.72
NDUFS4	4724	O43181	0.72
NDUFS5	4725	O43920	0.72
NDUFS6	4726	O75380	0.72
NDUFV2	4729	P19404	0.72
NDUFV3	4731	P56181	0.72
DDR2	4921	Q16832	0.72
PCDH7	5099	O60245	0.72
CHMP1A	5119	Q9HD42	0.72
PHB	5245	P35232	0.72
PHKA2	5256	P46019	0.72
HTRA1	5654	Q92743	0.72
ABCD3	5825	P28288	0.72
ALDH18A1	5832	P54886	0.72
RAB5C	5878	P51148	0.72
RECQL	5965	P46063	0.72
SNTB2	6645	Q13425	0.72
SOAT1	6646	P35610	0.72
TFRC	7037	P02786	0.72
TGFBR1	7046	P36897	0.72
TPI1	7167	P60174	0.72
UQCRC1	7384	P31930	0.72
UQCRC2	7385	P22695	0.72
UQCRFS1	7386	P47985	0.72
VDAC1	7416	P21796	0.72
VDAC2	7417	P45880	0.72
CXCR4	7852	P61073	0.72
GPRC5A	9052	Q8NFJ5	0.72
ATP6V0D1	9114	P61421	0.72
HGS	9146	O14964	0.72
XPR1	9213	Q9UBH6	0.72
VAPB	9217	O95292	0.72
VAPA	9218	Q9P0L0	0.72
RAB11B	9230	Q15907	0.72
ATP6V1F	9296	Q16864	0.72
COX5A	9377	P20674	0.72
ABCG2	9429	Q9UNQ0	0.72
PTGES	9536	O14684	0.72
ATP6V1G1	9550	O75348	0.72
SEC22B	9554	O75396	0.72
MLEC	9761	Q14165	0.72
PIEZO1	9780	Q92508	0.72
SPCS2	9789	Q15005	0.72
IST1	9798	P53990	0.72
PDCD6IP	10015	Q8WUM4	0.72
PDCD6	10016	O75340	0.72
BCAP31	10134	P51572	0.72
FLOT1	10211	O75955	0.72
TCIRG1	10312	Q13488	0.72
HYOU1	10525	Q9Y4L1	0.72
RABAC1	10567	Q9UI14	0.72
ERLIN1	10613	O75477	0.72
CKAP4	10970	Q07065	0.72
IMMT	10989	Q16891	0.72
ERLIN2	11160	O94905	0.72
PHB2	11331	Q99623	0.72
CHSY1	22856	Q86X52	0.72
ENDOD1	23052	O94919	0.72
SUN2	25777	Q9UH99	0.72
INTS7	25896	Q9NVH2	0.72
CHMP2B	25978	Q9UQN3	0.72
DHRS7B	25979	Q6IAN0	0.72
LRP10	26020	Q7Z4F1	0.72
MYOF	26509	Q9NZM1	0.72
ATP2C1	27032	P98194	0.72
UQCRQ	27089	O14949	0.72
GOLIM4	27333	O00461	0.72
ASTE1	28990	Q2TB18	0.72
STOML2	30968	Q9UJZ1	0.72
ITSN2	50618	Q9NZM3	0.72
NDUFA13	51079	Q9P0J0	0.72
ATP6V1D	51382	Q9Y5K8	0.72
FAM8A1	51439	Q9UBU6	0.72
ATP6V1H	51606	Q9UI12	0.72
SARAF	51669	Q96BY9	0.72
SLC38A2	54407	Q96QD8	0.72
CHCHD3	54927	Q9NX63	0.72
DNAJC11	55735	Q9NVH1	0.72
PLGRKT	55848	Q9HBL7	0.72
NDUFA12	55967	Q9UI09	0.72
KIDINS220	57498	Q9ULH0	0.72
NCKAP5L	57701	Q9HCH0	0.72
MRPL14	64928	Q6P1L8	0.72
TMEM237	65062	Q96Q45	0.72
FUNDC2	65991	Q9BWH2	0.72
VKORC1	79001	Q9BQB6	0.72
TMEM109	79073	Q9BVC6	0.72
MBOAT7	79143	Q96N66	0.72
TMEM43	79188	Q9BTV4	0.72
CYBRD1	79901	Q53TN4	0.72
REEP4	80346	Q9H6H4	0.72
LNP	80856	Q9C0E8	0.72
SGPP1	81537	Q9BX95	0.72
YIPF5	81555	Q969M3	0.72
CHCHD6	84303	Q9BRQ6	0.72
CCDC115	84317	Q96NT0	0.72
MCU	90550	Q8NE86	0.72
TMEM55B	90809	Q86T03	0.72
RNF185	91445	Q96GF1	0.72
ACBD5	91452	Q5T8D3	0.72
MMGT1	93380	Q8N4V1	0.72
PRKCDBP	112464	Q969G5	0.72
OSBPL8	114882	Q9BZF1	0.72
CHMP4B	128866	Q9H444	0.72
PTRF	284119	Q6NZI2	0.72
RABL3	285282	Q5HYI8	0.72
UBAC2	337867	Q8NBM4	0.72
C6orf120	387263	Q7Z4R8	0.72
TCTN3	26123	Q6NUS6	0.49
TMEM216	51259	Q9P0N5	0.49
ELAVL1	1994	Q15717	0.63
RTN4	57142	Q9NQC3	0.63
UNC93B1	81622	Q9H1C4	0.63
REEP5	7905	Q00765	0.72
KATNA1	11104	O75449	0.72
NABP1	64859	Q96AH0	0.72