Protein Description

Gene Symbol OSGIN1
Entrez ID 29948
Uniprot ID Q9UJX0
Description oxidative stress induced growth inhibitor 1
Chromosomal Location chr16: 83,948,282-83,966,332
Ontology GO ID GO Term Definition Evidence

BP

GO:0007275

multicellular organism development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

IEA

BP

GO:0030154

cell differentiation

The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

IEA

BP

GO:0030308

negative regulation of cell growth

Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.

IDA

BP

GO:0043065

positive regulation of apoptotic process

Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.

IEA

BP

GO:0055114

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

IEA

CC

GO:0005575

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

ND

MF

GO:0008083

growth factor activity

The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.

IDA

MF

GO:0016491

oxidoreductase activity

Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

IEA

Domain ID Description

IPR023753

FAD/NAD(P)-binding domain

IPR029724

Oxidative stress-induced growth inhibitor 1

IPR029731

OKL38 family

No pathways found.

No diseases found.

No tissues found.

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

AKT1

207

P31749

0.63

FGFR4

2264

P22455

0.63

KRAS

3845

P01116

0.63

PTEN

5728

P60484

0.63

XRCC3

7517

O43542

0.63

BCAR3

8412

O75815

0.63

PPM1D

8493

O15297

0.63

RPS6KA6

27330

Q9UK32

0.63

BTBD1

53339

Q9H0C5

0.63

BTBD2

55643

Q9BX70

0.63

CCDC33

80125

Q8N5R6

0.63

LNX1

84708

Q8TBB1

0.63

SAXO1

158297

Q8IYX7

0.63

INCA1

388324

Q0VD86

0.63

AES

166

Q08117

0.63

ATM

472

Q13315

0.63

CAPN3

825

P20807

0.63

CRX

1406

O43186

0.63

MEIS2

4212

O14770

0.63

MEOX2

4223

P50222

0.63

REL

5966

Q04864

0.63

SHMT2

6472

P34897

0.63

TCF4

6925

P15884

0.63

TCF12

6938

Q99081

0.63

DNAJA3

9093

Q96EY1

0.63

IKZF3

22806

Q9UKT9

0.63