| Gene Symbol | COL4A6 |
| Entrez ID | 1288 |
| Uniprot ID | Q14031 |
| Description | collagen, type IV, alpha 6 |
| Chromosomal Location | chrX: 108,155,607-108,439,497 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0007155 | cell adhesion |
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. | IEA |
BP | GO:0030198 | extracellular matrix organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. | TAS |
BP | GO:0030574 | collagen catabolic process |
The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells. | TAS |
CC | GO:0005576 | extracellular region |
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. | TAS |
CC | GO:0005587 | collagen type IV trimer |
A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes. | NAS |
CC | GO:0005788 | endoplasmic reticulum lumen |
The volume enclosed by the membranes of the endoplasmic reticulum. | TAS |
MF | GO:0005201 | extracellular matrix structural constituent |
The action of a molecule that contributes to the structural integrity of the extracellular matrix. | IEA |
| Domain ID | Description |
|---|---|
IPR001442 | Collagen IV, non-collagenous |
IPR008160 | Collagen triple helix repeat |
IPR016187 | C-type lectin fold |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
hsa04151 | PI3K-Akt signaling pathway | KEGG |
hsa04510 | Focal adhesion | KEGG |
hsa04512 | ECM-receptor interaction | KEGG |
hsa04933 | AGE-RAGE signaling pathway in diabetic complications | KEGG |
hsa04974 | Protein digestion and absorption | KEGG |
hsa05146 | Amoebiasis | KEGG |
hsa05200 | Pathways in cancer | KEGG |
hsa05222 | Small cell lung cancer | KEGG |
WP306 | Focal Adhesion | WikiPathways |
WP3932 | Focal Adhesion-PI3K-Akt-mTOR-signaling pathway | WikiPathways |
h_amiPathway | Acute Myocardial Infarction | BioCarta |
h_ace2Pathway | Angiotensin-converting enzyme 2 regulates heart function | BioCarta |
h_intrinsicPathway | Intrinsic Prothrombin Activation Pathway | BioCarta |
h_plateletAppPathway | Platelet Amyloid Precursor Protein Pathway | BioCarta |
h_npp1Pathway | Regulators of Bone Mineralization | BioCarta |
h_vitCBPathway | Vitamin C in the Brain | BioCarta |
| UMLS CUI | UMLS Term |
|---|---|
C0000786 | Spontaneous Abortion |
C0086533 | Leiomyoma, Epithelioid |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
15308691 | Jansen et al. | 2004 | Abnormal Gene Expression Profiles in Human Ovaries from Polycystic Ovary Syndrome Patients |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
SUMF1 | 285362 | Q8NBK3 | 0.49 |
FN1 | 2335 | P02751 | 0.52 |
DCN | 1634 | P07585 | 0.62 |
FBLN2 | 2199 | P98095 | 0.62 |
MMP9 | 4318 | P14780 | 0.62 |
SERPINE2 | 5270 | P07093 | 0.62 |
CD93 | 22918 | Q9NPY3 | 0.65 |
OSM | 5008 | P13725 | 0.66 |
KLK6 | 5653 | Q92876 | 0.68 |
APP | 351 | P05067 | 0.7 |
COL4A5 | 1287 | P29400 | 0.52 |
HABP2 | 3026 | Q14520 | 0.52 |
MATN2 | 4147 | O00339 | 0.62 |
VHL | 7428 | P40337 | 0.63 |