| Gene Symbol | COL4A6 |
| Entrez ID | 1288 |
| Uniprot ID | Q14031 |
| Description | collagen, type IV, alpha 6 |
| Chromosomal Location | chrX: 108,155,607-108,439,497 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0007155 |
cell adhesion |
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. |
IEA |
|
BP |
GO:0030198 |
extracellular matrix organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. |
TAS |
|
BP |
GO:0030574 |
collagen catabolic process |
The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells. |
TAS |
|
CC |
GO:0005576 |
extracellular region |
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
TAS |
|
CC |
GO:0005587 |
collagen type IV trimer |
A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes. |
NAS |
|
CC |
GO:0005788 |
endoplasmic reticulum lumen |
The volume enclosed by the membranes of the endoplasmic reticulum. |
TAS |
|
MF |
GO:0005201 |
extracellular matrix structural constituent |
The action of a molecule that contributes to the structural integrity of the extracellular matrix. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR001442 |
Collagen IV, non-collagenous |
|
IPR008160 |
Collagen triple helix repeat |
|
IPR016187 |
C-type lectin fold |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa04151 |
PI3K-Akt signaling pathway |
KEGG |
|
hsa04510 |
Focal adhesion |
KEGG |
|
hsa04512 |
ECM-receptor interaction |
KEGG |
|
hsa04933 |
AGE-RAGE signaling pathway in diabetic complications |
KEGG |
|
hsa04974 |
Protein digestion and absorption |
KEGG |
|
hsa05146 |
Amoebiasis |
KEGG |
|
hsa05200 |
Pathways in cancer |
KEGG |
|
hsa05222 |
Small cell lung cancer |
KEGG |
|
WP306 |
Focal Adhesion |
WikiPathways |
|
WP3932 |
Focal Adhesion-PI3K-Akt-mTOR-signaling pathway |
WikiPathways |
|
h_amiPathway |
Acute Myocardial Infarction |
BioCarta |
|
h_ace2Pathway |
Angiotensin-converting enzyme 2 regulates heart function |
BioCarta |
|
h_intrinsicPathway |
Intrinsic Prothrombin Activation Pathway |
BioCarta |
|
h_plateletAppPathway |
Platelet Amyloid Precursor Protein Pathway |
BioCarta |
|
h_npp1Pathway |
Regulators of Bone Mineralization |
BioCarta |
|
h_vitCBPathway |
Vitamin C in the Brain |
BioCarta |
| UMLS CUI | UMLS Term |
|---|---|
|
C0000786 |
Spontaneous Abortion |
|
C0086533 |
Leiomyoma, Epithelioid |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
15308691 |
Jansen et al. |
2004 |
Abnormal Gene Expression Profiles in Human Ovaries from Polycystic Ovary Syndrome Patients |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
SUMF1 |
285362 |
Q8NBK3 |
0.49 |
|
FN1 |
2335 |
P02751 |
0.52 |
|
DCN |
1634 |
P07585 |
0.62 |
|
FBLN2 |
2199 |
P98095 |
0.62 |
|
MMP9 |
4318 |
P14780 |
0.62 |
|
SERPINE2 |
5270 |
P07093 |
0.62 |
|
CD93 |
22918 |
Q9NPY3 |
0.65 |
|
OSM |
5008 |
P13725 |
0.66 |
|
KLK6 |
5653 |
Q92876 |
0.68 |
|
APP |
351 |
P05067 |
0.70 |
|
COL4A5 |
1287 |
P29400 |
0.52 |
|
HABP2 |
3026 |
Q14520 |
0.52 |
|
MATN2 |
4147 |
O00339 |
0.62 |
|
VHL |
7428 |
P40337 |
0.63 |