| Gene Symbol | CARD10 |
| Entrez ID | 29775 |
| Uniprot ID | Q9BWT7 |
| Description | caspase recruitment domain family member 10 |
| Chromosomal Location | chr22: 37,490,362-37,519,542 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006461 |
protein complex assembly |
The aggregation, arrangement and bonding together of a set of components to form a protein complex. |
NAS |
|
BP |
GO:0007250 |
activation of NF-kappaB-inducing kinase activity |
The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues. |
IDA|ISS |
|
BP |
GO:0042981 |
regulation of apoptotic process |
Any process that modulates the occurrence or rate of cell death by apoptotic process. |
IEA |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
NAS |
|
CC |
GO:0032449 |
CBM complex |
A protein complex comprising Carma1, Bcl10 and MALT1; plays a role in signal transduction during NF-kappaB activation. |
NAS |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0030159 |
receptor signaling complex scaffold activity |
Functions to provide a physical support for the assembly of a multiprotein receptor signaling complex. |
NAS |
| Domain ID | Description |
|---|---|
|
IPR001315 |
CARD domain |
|
IPR011029 |
Death-like domain |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa04064 |
NF-kappa B signaling pathway |
KEGG |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
glial cells |
|
cerebellum |
cells in granular layer |
|
cerebellum |
Purkinje cells |
|
cervix, uterine |
glandular cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
heart muscle |
myocytes |
|
kidney |
cells in tubules |
|
liver |
hepatocytes |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
pancreas |
exocrine glandular cells |
|
parathyroid gland |
glandular cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
fibroblasts |
|
small intestine |
glandular cells |
|
spleen |
cells in white pulp |
|
stomach |
glandular cells |
|
thyroid gland |
glandular cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
19141487 |
Kenigsberg et al. |
2009 |
Gene expression microarray profiles of cumulus cells in lean and overweightobese polycystic ovary syndrome patients |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
CARD10 |
29775 |
Q9BWT7 |
0.63 |
|
KLHL12 |
59349 |
Q53G59 |
0.63 |
|
IKBKG |
8517 |
Q9Y6K9 |
0.76 |
|
BCL10 |
8915 |
O95999 |
0.90 |
|
CDC5L |
988 |
Q99459 |
0.63 |
|
ATXN7 |
6314 |
O15265 |
0.63 |
|
GFOD1 |
54438 |
Q9NXC2 |
0.63 |
|
CAPZA2 |
830 |
P47755 |
0.72 |
|
DBN1 |
1627 |
Q16643 |
0.72 |
|
MYO1C |
4641 |
O00159 |
0.72 |
|
KIF20A |
10112 |
O95235 |
0.72 |
|
MYO19 |
80179 |
Q96H55 |
0.72 |