Gene Symbol | CARD10 |
Entrez ID | 29775 |
Uniprot ID | Q9BWT7 |
Description | caspase recruitment domain family member 10 |
Chromosomal Location | chr22: 37,490,362-37,519,542 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006461 |
protein complex assembly |
The aggregation, arrangement and bonding together of a set of components to form a protein complex. |
NAS |
BP |
GO:0007250 |
activation of NF-kappaB-inducing kinase activity |
The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues. |
IDA|ISS |
BP |
GO:0042981 |
regulation of apoptotic process |
Any process that modulates the occurrence or rate of cell death by apoptotic process. |
IEA |
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
NAS |
CC |
GO:0032449 |
CBM complex |
A protein complex comprising Carma1, Bcl10 and MALT1; plays a role in signal transduction during NF-kappaB activation. |
NAS |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0030159 |
receptor signaling complex scaffold activity |
Functions to provide a physical support for the assembly of a multiprotein receptor signaling complex. |
NAS |
Domain ID | Description |
---|---|
IPR001315 |
CARD domain |
IPR011029 |
Death-like domain |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa04064 |
NF-kappa B signaling pathway |
KEGG |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
appendix |
glandular cells |
breast |
glandular cells |
breast |
myoepithelial cells |
bronchus |
respiratory epithelial cells |
caudate |
glial cells |
cerebellum |
cells in granular layer |
cerebellum |
Purkinje cells |
cervix, uterine |
glandular cells |
colon |
glandular cells |
duodenum |
glandular cells |
endometrium |
glandular cells |
epididymis |
glandular cells |
fallopian tube |
glandular cells |
gallbladder |
glandular cells |
heart muscle |
myocytes |
kidney |
cells in tubules |
liver |
hepatocytes |
lymph node |
non-germinal center cells |
nasopharynx |
respiratory epithelial cells |
pancreas |
exocrine glandular cells |
parathyroid gland |
glandular cells |
prostate |
glandular cells |
rectum |
glandular cells |
salivary gland |
glandular cells |
seminal vesicle |
glandular cells |
skin |
fibroblasts |
small intestine |
glandular cells |
spleen |
cells in white pulp |
stomach |
glandular cells |
thyroid gland |
glandular cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
19141487 |
Kenigsberg et al. |
2009 |
Gene expression microarray profiles of cumulus cells in lean and overweightobese polycystic ovary syndrome patients |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
CARD10 |
29775 |
Q9BWT7 |
0.63 |
KLHL12 |
59349 |
Q53G59 |
0.63 |
IKBKG |
8517 |
Q9Y6K9 |
0.76 |
BCL10 |
8915 |
O95999 |
0.90 |
CDC5L |
988 |
Q99459 |
0.63 |
ATXN7 |
6314 |
O15265 |
0.63 |
GFOD1 |
54438 |
Q9NXC2 |
0.63 |
CAPZA2 |
830 |
P47755 |
0.72 |
DBN1 |
1627 |
Q16643 |
0.72 |
MYO1C |
4641 |
O00159 |
0.72 |
KIF20A |
10112 |
O95235 |
0.72 |
MYO19 |
80179 |
Q96H55 |
0.72 |