Protein Description

Gene Symbol GOLIM4
Entrez ID 27333
Uniprot ID O00461
Description golgi integral membrane protein 4
Chromosomal Location chr3: 168,008,677-168,095,975
Ontology GO ID GO Term Definition Evidence

BP

GO:0006810

transport

The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.

IEA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

TAS

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

IDA

CC

GO:0005794

Golgi apparatus

A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.

IDA

CC

GO:0005796

Golgi lumen

The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.

TAS

CC

GO:0005801

cis-Golgi network

The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.

TAS

CC

GO:0010008

endosome membrane

The lipid bilayer surrounding an endosome.

IEA

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

CC

GO:0030133

transport vesicle

Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.

TAS

CC

GO:0030139

endocytic vesicle

A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.

TAS

CC

GO:0032580

Golgi cisterna membrane

The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.

IEA

No domains found.

No pathways found.

No diseases found.

Tissue Cell Type

appendix

glandular cells

bone marrow

hematopoietic cells

breast

glandular cells

cerebellum

Purkinje cells

cerebral cortex

neuronal cells

colon

glandular cells

duodenum

glandular cells

endometrium

glandular cells

gallbladder

glandular cells

heart muscle

myocytes

liver

bile duct cells

liver

hepatocytes

nasopharynx

respiratory epithelial cells

pancreas

islets of Langerhans

placenta

decidual cells

rectum

glandular cells

small intestine

glandular cells

smooth muscle

smooth muscle cells

spleen

cells in red pulp

stomach

glandular cells

tonsil

germinal center cells

tonsil

non-germinal center cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

TXN2

25828

Q99757

0.49

DDX5

1655

P17844

0.49

ATP1A1

476

P05023

0.63

ELAVL1

1994

Q15717

0.63

FUS

2521

P35637

0.63

HLA-DPA1

3113

P20036

0.63

NTRK1

4914

P04629

0.63

B3GAT3

26229

O94766

0.63

HAUS7

55559

Q99871

0.63

SLC39A4

55630

Q6P5W5

0.63

SPACA1

81833

Q9HBV2

0.63

POMK

84197

Q9H5K3

0.63

SYNE4

163183

Q8N205

0.63

CDC42

998

P60953

0.72

EPHA2

1969

P29317

0.72

KRAS

3845

P01116

0.72

PTPN1

5770

P18031

0.72

IQGAP1

8826

P46940

0.72

VAPA

9218

Q9P0L0

0.72

ATP6AP2

10159

O75787

0.72

FGFR1OP

11116

O95684

0.72

AP4S1

11154

Q9Y587

0.72

AP4E1

23431

Q9UPM8

0.72

GOLT1B

51026

Q9Y3E0

0.72

VPS50

55610

Q96JG6

0.72

PARD6B

84612

Q9BYG5

0.72

MMGT1

93380

Q8N4V1

0.72