Protein Description

Gene Symbol ZNF638
Entrez ID 27332
Uniprot ID Q14966
Description zinc finger protein 638
Chromosomal Location chr2: 71,276,561-71,435,069
Ontology GO ID GO Term Definition Evidence

BP

GO:0006351

transcription, DNA-templated

The cellular synthesis of RNA on a template of DNA.

IEA

BP

GO:0006355

regulation of transcription, DNA-templated

Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

IEA

BP

GO:0008380

RNA splicing

The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.

IEA

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

IDA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

TAS

CC

GO:0016607

nuclear speck

A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.

IEA

CC

GO:0043231

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

IDA

MF

GO:0000166

nucleotide binding

Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.

IEA

MF

GO:0003690

double-stranded DNA binding

Interacting selectively and non-covalently with double-stranded DNA.

TAS

MF

GO:0003723

RNA binding

Interacting selectively and non-covalently with an RNA molecule or a portion thereof.

TAS

MF

GO:0008270

zinc ion binding

Interacting selectively and non-covalently with zinc (Zn) ions.

IEA

MF

GO:0044822

poly(A) RNA binding

Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.

IDA

Domain ID Description

IPR000504

RNA recognition motif domain

IPR000690

Matrin/U1-C, C2H2-type zinc finger

IPR003604

Matrin/U1-C-like, C2H2-type zinc finger

IPR013087

Zinc finger C2H2-type

IPR022755

Zinc finger, double-stranded RNA binding

IPR033096

Zinc finger protein 638

No pathways found.

No diseases found.

Tissue Cell Type

breast

glandular cells

breast

myoepithelial cells

bronchus

respiratory epithelial cells

caudate

neuronal cells

cerebellum

cells in granular layer

cerebellum

cells in molecular layer

cerebellum

Purkinje cells

cerebral cortex

glial cells

cerebral cortex

neuronal cells

colon

glandular cells

colon

peripheral nerve/ganglion

duodenum

glandular cells

gallbladder

glandular cells

kidney

cells in tubules

nasopharynx

respiratory epithelial cells

placenta

decidual cells

rectum

glandular cells

small intestine

glandular cells

testis

cells in seminiferous ducts

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

ZNF24

7572

P17028

0.49

SF3A3

10946

Q12874

0.49

NELFCD

51497

Q8IXH7

0.63

CCDC85B

11007

Q15834

0.73

KIF1BP

26128

Q96EK5

0.73

KRTAP4-12

83755

Q9BQ66

0.73

FHL2

2274

Q14192

0.78

GTF2F2

2963

P13984

0.49

PURA

5813

Q00577

0.49

YY1

7528

P25490

0.49

WASL

8976

O00401

0.49

ESR2

2100

Q92731

0.55

SUMO1

7341

P63165

0.56

BMI1

648

P35226

0.63

CDC5L

988

Q99459

0.63

ELAVL1

1994

Q15717

0.63

EZH2

2146

Q15910

0.63

IFI16

3428

Q16666

0.63

JUN

3725

P05412

0.63

KRT15

3866

P19012

0.63

KRT19

3880

P08727

0.63

RNF2

6045

Q99496

0.63

RPA1

6117

P27694

0.63

RPA2

6118

P15927

0.63

RPA3

6119

P35244

0.63

SPP1

6696

P10451

0.63

YWHAG

7532

P61981

0.63

EED

8726

O75530

0.63

CUL7

9820

Q14999

0.63

CALCOCO2

10241

Q13137

0.63

SRRM1

10250

Q8IYB3

0.63

GABARAPL2

11345

P60520

0.63

SNW1

22938

Q13573

0.63

PASK

23178

Q96RG2

0.63

OBSL1

23363

O75147

0.63

MED4

29079

Q9NPJ6

0.63

HOOK2

29911

Q96ED9

0.63

SIRT7

51547

Q9NRC8

0.63

LGR4

55366

Q9BXB1

0.63

LUC7L

55692

Q9NQ29

0.63

CAND1

55832

Q86VP6

0.63

HECW2

57520

Q9P2P5

0.63

MAP1LC3A

84557

Q9H492

0.63

HNRNPA1

3178

P09651

0.72

PPP1CB

5500

P62140

0.72

PPP1CC

5501

P36873

0.72

MATR3

9782

P43243

0.72

MPHOSPH8

54737

Q99549

0.72

PLSCR1

5359

O15162

0.73

WWP1

11059

Q9H0M0

0.73

EFEMP2

30008

O95967

0.73

SFN

2810

P31947

0.76