BP

GO:0007399

nervous system development

The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

ISS

BP

GO:0008589

regulation of smoothened signaling pathway

Any process that modulates the frequency, rate or extent of smoothened signaling.

ISS

BP

GO:0010839

negative regulation of keratinocyte proliferation

Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.

IEA

BP

GO:0021513

spinal cord dorsal/ventral patterning

The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.

IEA

BP

GO:0021915

neural tube development

The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.

IEA

BP

GO:0030216

keratinocyte differentiation

The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.

IEA

BP

GO:0030278

regulation of ossification

Any process that modulates the frequency, rate or extent of bone formation.

IEA

BP

GO:0031069

hair follicle morphogenesis

The process in which the anatomical structures of the hair follicle are generated and organized.

IEA

BP

GO:0042384

cilium assembly

The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.

ISS

BP

GO:0042733

embryonic digit morphogenesis

The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe.

IEA

BP

GO:0045880

positive regulation of smoothened signaling pathway

Any process that activates or increases the frequency, rate or extent of smoothened signaling.

IEA

BP

GO:0051782

negative regulation of cell division

Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.

IEA

BP

GO:0060173

limb development

The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.

ISS

BP

GO:1903887

motile primary cilium assembly

The aggregation, arrangement and bonding together of a set of components to form a motile primary cilium.

IEA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

ISS

CC

GO:0009986

cell surface

The external part of the cell wall and/or plasma membrane.

IEA

CC

GO:0031514

motile cilium

A cilium which has a variable arrangement of axonemal microtubules, contains molecular motors, and beats with a characteristic whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface. Motile cilia are typically found in multiple copies on epithelial cells that line the lumenal ducts of various tissues. Motile cilia may also function as sensory organelles.

IDA

CC

GO:0036064

ciliary basal body

A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.

IDA