| Gene Symbol | CPAMD8 |
| Entrez ID | 27151 |
| Uniprot ID | Q8IZJ3 |
| Description | C3 and PZP-like, alpha-2-macroglobulin domain containing 8 |
| Chromosomal Location | chr19: 16,892,947-17,026,815 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0010951 |
negative regulation of endopeptidase activity |
Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins. |
IEA |
|
CC |
GO:0005615 |
extracellular space |
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
IEA |
|
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
IEA |
|
MF |
GO:0004867 |
serine-type endopeptidase inhibitor activity |
Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR001599 |
Alpha-2-macroglobulin |
|
IPR002350 |
Kazal domain |
|
IPR002890 |
Alpha-2-macroglobulin, N-terminal |
|
IPR008930 |
Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid |
|
IPR009048 |
Alpha-macroglobulin, receptor-binding |
|
IPR011625 |
Alpha-2-macroglobulin, N-terminal 2 |
|
IPR011626 |
Alpha-macroglobulin complement component |
|
IPR013783 |
Immunoglobulin-like fold |
|
IPR014756 |
Immunoglobulin E-set |
|
IPR019565 |
Alpha-2-macroglobulin, thiol-ester bond-forming |
|
IPR019742 |
Alpha-2-macroglobulin, conserved site |
|
IPR022041 |
Farnesoic acid O-methyl transferase |
| UMLS CUI | UMLS Term |
|---|---|
|
C0009404 |
Colorectal Neoplasms |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
cerebellum |
Purkinje cells |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
heart muscle |
myocytes |
|
kidney |
cells in tubules |
|
lung |
macrophages |
|
nasopharynx |
respiratory epithelial cells |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
melanocytes |
|
soft tissue |
adipocytes |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
DPP4 |
1803 |
P27487 |
0.52 |
|
SCTR |
6344 |
P47872 |
0.67 |
|
ADCYAP1 |
116 |
P18509 |
0.63 |