Protein Description

Gene Symbol NSG1
Entrez ID 27065
Uniprot ID P42857
Description neuron specific gene family member 1
Chromosomal Location chr4: 4,348,140-4,419,058
Ontology GO ID GO Term Definition Evidence

BP

GO:0001921

positive regulation of receptor recycling

Any process that activates or increases the frequency, rate or extent of receptor recycling.

IEA

BP

GO:0007212

dopamine receptor signaling pathway

The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.

IEA

BP

GO:0016197

endosomal transport

The directed movement of substances into, out of, or mediated by an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation.

IEA

BP

GO:0048268

clathrin coat assembly

The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage.

IEA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

IEA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

TAS

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

TAS

CC

GO:0005768

endosome

A vacuole to which materials ingested by endocytosis are delivered.

IEA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

CC

GO:0016328

lateral plasma membrane

The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells.

IEA

CC

GO:0045211

postsynaptic membrane

A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.

IEA

MF

GO:0005102

receptor binding

Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0032051

clathrin light chain binding

Interacting selectively and non-covalently with a clathrin light chain.

IEA

Domain ID Description

IPR009431

Calcyon neuron-specific vesicular protein

No pathways found.

No diseases found.

Tissue Cell Type

adrenal gland

glandular cells

bone marrow

hematopoietic cells

lung

macrophages

testis

cells in seminiferous ducts

No databases found.

Pubmed ID Author Year Title

19141487

Kenigsberg et al.

2009

Gene expression microarray profiles of cumulus cells in lean and overweightobese polycystic ovary syndrome patients

19141577

Kim et al.

2009

Transcriptional Profiling with a Pathway-Oriented Analysis Identifies Dysregulated Molecular Phenotypes in the Endometrium of Patients with Polycystic Ovary Syndrome

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

STX12

23673

Q86Y82

0.52

CCDC155

147872

Q8N6L0

0.63

BSCL2

26580

Q96G97

0.63

SRPK1

6732

Q96SB4

0.72

SRPK2

6733

P78362

0.72