| Gene Symbol | PCOLCE2 |
| Entrez ID | 26577 |
| Uniprot ID | Q9UKZ9 |
| Description | procollagen C-endopeptidase enhancer 2 |
| Chromosomal Location | chr3: 142,815,922-142,889,203 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0010952 |
positive regulation of peptidase activity |
Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. |
IEA |
|
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
|
MF |
GO:0005518 |
collagen binding |
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). |
IDA |
|
MF |
GO:0008201 |
heparin binding |
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. |
IDA |
|
MF |
GO:0016504 |
peptidase activator activity |
Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR000859 |
CUB domain |
|
IPR001134 |
Netrin domain |
|
IPR008993 |
Tissue inhibitor of metalloproteinases-like, OB-fold |
|
IPR018933 |
Netrin module, non-TIMP type |
| UMLS CUI | UMLS Term |
|---|---|
|
C0236733 |
Amphetamine-Related Disorders |
| Tissue | Cell Type |
|---|---|
|
appendix |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
cells in endometrial stroma |
|
esophagus |
squamous epithelial cells |
|
kidney |
cells in glomeruli |
|
placenta |
trophoblastic cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
stomach |
glandular cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
|
23824412 |
Piltonen et al. |
2013 |
Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
STRN |
6801 |
O43815 |
0.63 |
|
ZWINT |
11130 |
O95229 |
0.63 |
|
STRN4 |
29888 |
Q9NRL3 |
0.63 |
|
STRN3 |
29966 |
Q13033 |
0.63 |
|
OLFM1 |
10439 |
Q99784 |
0.63 |
|
SUSD4 |
55061 |
Q5VX71 |
0.63 |