Gene Symbol | PCOLCE2 |
Entrez ID | 26577 |
Uniprot ID | Q9UKZ9 |
Description | procollagen C-endopeptidase enhancer 2 |
Chromosomal Location | chr3: 142,815,922-142,889,203 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0010952 |
positive regulation of peptidase activity |
Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. |
IEA |
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
MF |
GO:0005518 |
collagen binding |
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). |
IDA |
MF |
GO:0008201 |
heparin binding |
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. |
IDA |
MF |
GO:0016504 |
peptidase activator activity |
Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. |
IDA |
Domain ID | Description |
---|---|
IPR000859 |
CUB domain |
IPR001134 |
Netrin domain |
IPR008993 |
Tissue inhibitor of metalloproteinases-like, OB-fold |
IPR018933 |
Netrin module, non-TIMP type |
UMLS CUI | UMLS Term |
---|---|
C0236733 |
Amphetamine-Related Disorders |
Tissue | Cell Type |
---|---|
appendix |
glandular cells |
bronchus |
respiratory epithelial cells |
colon |
glandular cells |
duodenum |
glandular cells |
endometrium |
cells in endometrial stroma |
esophagus |
squamous epithelial cells |
kidney |
cells in glomeruli |
placenta |
trophoblastic cells |
rectum |
glandular cells |
salivary gland |
glandular cells |
stomach |
glandular cells |
tonsil |
squamous epithelial cells |
urinary bladder |
urothelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
23824412 |
Piltonen et al. |
2013 |
Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
STRN |
6801 |
O43815 |
0.63 |
ZWINT |
11130 |
O95229 |
0.63 |
STRN4 |
29888 |
Q9NRL3 |
0.63 |
STRN3 |
29966 |
Q13033 |
0.63 |
OLFM1 |
10439 |
Q99784 |
0.63 |
SUSD4 |
55061 |
Q5VX71 |
0.63 |