| Gene Symbol | PCOLCE2 |
| Entrez ID | 26577 |
| Uniprot ID | Q9UKZ9 |
| Description | procollagen C-endopeptidase enhancer 2 |
| Chromosomal Location | chr3: 142,815,922-142,889,203 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0010952 | positive regulation of peptidase activity |
Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. | IEA |
CC | GO:0070062 | extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. | IDA |
MF | GO:0005518 | collagen binding |
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). | IDA |
MF | GO:0008201 | heparin binding |
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. | IDA |
MF | GO:0016504 | peptidase activator activity |
Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. | IDA |
| Domain ID | Description |
|---|---|
IPR000859 | CUB domain |
IPR001134 | Netrin domain |
IPR008993 | Tissue inhibitor of metalloproteinases-like, OB-fold |
IPR018933 | Netrin module, non-TIMP type |
| UMLS CUI | UMLS Term |
|---|---|
C0236733 | Amphetamine-Related Disorders |
| Tissue | Cell Type |
|---|---|
appendix | glandular cells |
bronchus | respiratory epithelial cells |
colon | glandular cells |
duodenum | glandular cells |
endometrium | cells in endometrial stroma |
esophagus | squamous epithelial cells |
kidney | cells in glomeruli |
placenta | trophoblastic cells |
rectum | glandular cells |
salivary gland | glandular cells |
stomach | glandular cells |
tonsil | squamous epithelial cells |
urinary bladder | urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22951915 | Haozi et al. | 2012 | Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
23824412 | Piltonen et al. | 2013 | Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
STRN | 6801 | O43815 | 0.63 |
ZWINT | 11130 | O95229 | 0.63 |
STRN4 | 29888 | Q9NRL3 | 0.63 |
STRN3 | 29966 | Q13033 | 0.63 |
OLFM1 | 10439 | Q99784 | 0.63 |
SUSD4 | 55061 | Q5VX71 | 0.63 |