| Gene Symbol | PPP1R14B |
| Entrez ID | 26472 |
| Uniprot ID | Q96C90 |
| Description | protein phosphatase 1 regulatory inhibitor subunit 14B |
| Chromosomal Location | chr11: 64,244,480-64,246,941 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0035304 |
regulation of protein dephosphorylation |
Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein. |
IBA |
|
BP |
GO:0042325 |
regulation of phosphorylation |
Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule. |
IEA |
|
BP |
GO:0043086 |
negative regulation of catalytic activity |
Any process that stops or reduces the activity of an enzyme. |
IBA |
|
BP |
GO:0045087 |
innate immune response |
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. |
IBA |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IEA |
|
MF |
GO:0004865 |
protein serine/threonine phosphatase inhibitor activity |
Stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate. |
IBA |
| Domain ID | Description |
|---|---|
|
IPR008025 |
PKC-activated phosphatase-1 inhibitor |
| UMLS CUI | UMLS Term |
|---|---|
|
C0025202 |
Melanoma |
| Tissue | Cell Type |
|---|---|
|
appendix |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
cerebellum |
cells in granular layer |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
endothelial cells |
|
colon |
glandular cells |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
heart muscle |
myocytes |
|
kidney |
cells in tubules |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
pancreas |
exocrine glandular cells |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
fibroblasts |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
smooth muscle |
smooth muscle cells |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
thyroid gland |
glandular cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |