Gene Symbol | PITPNC1 |
Entrez ID | 26207 |
Uniprot ID | Q9UKF7 |
Description | phosphatidylinositol transfer protein, cytoplasmic 1 |
Chromosomal Location | chr17: 67,377,281-67,697,261 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0007165 |
signal transduction |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
IMP |
BP |
GO:0015914 |
phospholipid transport |
The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester. |
IDA |
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA |
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0008526 |
phosphatidylinositol transporter activity |
Enables the directed movement of phosphatidylinositol into, out of or within a cell, or between cells. Phosphatidylinositol refers to any glycophospholipids with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. |
IDA|IMP |
MF |
GO:0035091 |
phosphatidylinositol binding |
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives. |
IDA |
MF |
GO:0070300 |
phosphatidic acid binding |
Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids. |
IDA |
MF |
GO:1901611 |
phosphatidylglycerol binding |
Interacting selectively and non-covalently with phosphatidylglycerol. |
IDA |
Domain ID | Description |
---|---|
IPR001666 |
Phosphatidylinositol transfer protein |
IPR023393 |
START-like domain |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
breast |
glandular cells |
bronchus |
respiratory epithelial cells |
caudate |
glial cells |
caudate |
neuronal cells |
cerebral cortex |
neuronal cells |
cerebral cortex |
neuropil |
cervix, uterine |
glandular cells |
colon |
glandular cells |
endometrium |
glandular cells |
esophagus |
squamous epithelial cells |
gallbladder |
glandular cells |
hippocampus |
neuronal cells |
lung |
macrophages |
nasopharynx |
respiratory epithelial cells |
salivary gland |
glandular cells |
skeletal muscle |
myocytes |
small intestine |
glandular cells |
smooth muscle |
smooth muscle cells |
thyroid gland |
glandular cells |
vagina |
squamous epithelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
CMTM5 |
116173 |
Q96DZ9 |
0.63 |
AGTRAP |
57085 |
Q6RW13 |
0.74 |