Protein Description

Gene Symbol MTG2
Entrez ID 26164
Uniprot ID Q9H4K7
Description mitochondrial ribosome-associated GTPase 2
Chromosomal Location chr20: 62,183,029-62,203,568
Ontology GO ID GO Term Definition Evidence

BP

GO:0042254

ribosome biogenesis

A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.

IEA

BP

GO:0044065

regulation of respiratory system process

Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system.

IMP

BP

GO:0070129

regulation of mitochondrial translation

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.

IMP

CC

GO:0005743

mitochondrial inner membrane

The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

IDA

CC

GO:0005759

mitochondrial matrix

The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

IDA

CC

GO:0005761

mitochondrial ribosome

A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.

IDA

MF

GO:0000287

magnesium ion binding

Interacting selectively and non-covalently with magnesium (Mg) ions.

IEA

MF

GO:0003924

GTPase activity

Catalysis of the reaction: GTP + H2O = GDP + phosphate.

IDA

MF

GO:0005525

GTP binding

Interacting selectively and non-covalently with GTP, guanosine triphosphate.

IEA

Domain ID Description

IPR005225

Small GTP-binding protein domain

IPR006073

GTP binding domain

IPR006169

GTP1/OBG domain

IPR014100

GTP-binding protein Obg/CgtA

IPR027417

P-loop containing nucleoside triphosphate hydrolase

IPR031167

OBG-type guanine nucleotide-binding (G) domain

No pathways found.

No diseases found.

Tissue Cell Type

cerebellum

cells in granular layer

cerebellum

cells in molecular layer

cerebellum

Purkinje cells

cerebral cortex

endothelial cells

cerebral cortex

neuronal cells

cerebral cortex

neuropil

hippocampus

glial cells

hippocampus

neuronal cells

prostate

glandular cells

soft tissue

chondrocytes

testis

Leydig cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

MAPK6

5597

Q16659

0.63

TAB1

10454

Q15750

0.63

OXLD1

339229

Q5BKU9

0.63