| Gene Symbol | RSL1D1 |
| Entrez ID | 26156 |
| Uniprot ID | O76021 |
| Description | ribosomal L1 domain containing 1 |
| Chromosomal Location | chr16: 11,833,850-11,851,585 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0000470 |
maturation of LSU-rRNA |
Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule. |
IBA |
|
BP |
GO:0001649 |
osteoblast differentiation |
The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone. |
IDA |
|
BP |
GO:0032880 |
regulation of protein localization |
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. |
IMP |
|
BP |
GO:0042981 |
regulation of apoptotic process |
Any process that modulates the occurrence or rate of cell death by apoptotic process. |
IDA |
|
BP |
GO:0098609 |
cell-cell adhesion |
The attachment of one cell to another cell via adhesion molecules. |
IEA |
|
BP |
GO:2000772 |
regulation of cellular senescence |
Any process that modulates the frequency, rate or extent of cellular senescence. |
IDA |
|
CC |
GO:0005730 |
nucleolus |
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
IDA |
|
CC |
GO:0005913 |
cell-cell adherens junction |
An adherens junction which connects a cell to another cell. |
IDA |
|
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
|
CC |
GO:0030686 |
90S preribosome |
A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins. |
IBA |
|
MF |
GO:0003723 |
RNA binding |
Interacting selectively and non-covalently with an RNA molecule or a portion thereof. |
IBA |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
|
MF |
GO:0098641 |
cadherin binding involved in cell-cell adhesion |
Any cadherin binding that occurs as part of the process of cell-cell adhesion. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR016095 |
Ribosomal protein L1, 3-layer alpha/beta-sandwich |
|
IPR023674 |
Ribosomal protein L1-like |
|
IPR028364 |
Ribosomal protein L1/ribosomal biogenesis protein |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
WP615 |
Senescence and Autophagy in Cancer |
WikiPathways |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
neuronal cells |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
hippocampus |
neuronal cells |
|
liver |
hepatocytes |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
follicle cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
rectum |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
fibroblasts |
|
skin |
keratinocytes |
|
skin |
Langerhans |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
IL7R |
3575 |
P16871 |
0.49 |
|
RPL4 |
6124 |
P36578 |
0.49 |
|
RPS7 |
6201 |
P62081 |
0.49 |
|
RPS13 |
6207 |
P62277 |
0.49 |
|
H1FX |
8971 |
Q92522 |
0.49 |
|
POLR3F |
10621 |
Q9H1D9 |
0.49 |
|
POLR3C |
10623 |
Q9BUI4 |
0.49 |
|
RRS1 |
23212 |
Q15050 |
0.49 |
|
ADH6 |
130 |
P28332 |
0.63 |
|
PDLIM5 |
10611 |
Q96HC4 |
0.63 |
|
CAB39 |
51719 |
Q9Y376 |
0.63 |
|
SNU13 |
4809 |
P55769 |
0.49 |
|
NOP2 |
4839 |
P46087 |
0.49 |
|
RPL19 |
6143 |
P84098 |
0.49 |
|
RPS11 |
6205 |
P62280 |
0.49 |
|
DDX21 |
9188 |
Q9NR30 |
0.49 |
|
NOLC1 |
9221 |
Q14978 |
0.49 |
|
RBM14 |
10432 |
Q96PK6 |
0.49 |
|
MYBBP1A |
10514 |
Q9BQG0 |
0.49 |
|
RRP12 |
23223 |
Q5JTH9 |
0.49 |
|
NCSTN |
23385 |
Q92542 |
0.49 |
|
HP1BP3 |
50809 |
Q5SSJ5 |
0.49 |
|
SRPK2 |
6733 |
P78362 |
0.52 |
|
APP |
351 |
P05067 |
0.56 |
|
FBL |
2091 |
P22087 |
0.56 |
|
DDX52 |
11056 |
Q9Y2R4 |
0.56 |
|
NOP58 |
51602 |
Q9Y2X3 |
0.56 |
|
BRCA1 |
672 |
P38398 |
0.63 |
|
CSNK1A1 |
1452 |
P48729 |
0.63 |
|
DHX8 |
1659 |
Q14562 |
0.63 |
|
FN1 |
2335 |
P02751 |
0.63 |
|
HIST1H1A |
3024 |
Q02539 |
0.63 |
|
IFI16 |
3428 |
Q16666 |
0.63 |
|
ITGA4 |
3676 |
P13612 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
MNDA |
4332 |
P41218 |
0.63 |
|
YBX1 |
4904 |
P67809 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
EIF2AK2 |
5610 |
P19525 |
0.63 |
|
SUMO3 |
6612 |
P55854 |
0.63 |
|
SUMO2 |
6613 |
P61956 |
0.63 |
|
SUMO1 |
7341 |
P63165 |
0.63 |
|
VCAM1 |
7412 |
P19320 |
0.63 |
|
YY1 |
7528 |
P25490 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
CUL1 |
8454 |
Q13616 |
0.63 |
|
EED |
8726 |
O75530 |
0.63 |
|
KIAA0101 |
9768 |
Q15004 |
0.63 |
|
CUL7 |
9820 |
Q14999 |
0.63 |
|
COPS5 |
10987 |
Q92905 |
0.63 |
|
GABARAP |
11337 |
O95166 |
0.63 |
|
GABARAPL2 |
11345 |
P60520 |
0.63 |
|
ZC3H3 |
23144 |
Q8IXZ2 |
0.63 |
|
OBSL1 |
23363 |
O75147 |
0.63 |
|
SUZ12 |
23512 |
Q15022 |
0.63 |
|
GABARAPL1 |
23710 |
Q9H0R8 |
0.63 |
|
AGO1 |
26523 |
Q9UL18 |
0.63 |
|
MED4 |
29079 |
Q9NPJ6 |
0.63 |
|
SIRT7 |
51547 |
Q9NRC8 |
0.63 |
|
LYAR |
55646 |
Q9NX58 |
0.63 |
|
RIOK2 |
55781 |
Q9BVS4 |
0.63 |
|
CAND1 |
55832 |
Q86VP6 |
0.63 |
|
NIFK |
84365 |
Q9BYG3 |
0.63 |
|
PYHIN1 |
149628 |
Q6K0P9 |
0.63 |
|
MED19 |
219541 |
A0JLT2 |
0.63 |
|
ESR1 |
2099 |
P03372 |
0.67 |
|
CSNK2A1 |
1457 |
P68400 |
0.70 |
|
HDGF |
3068 |
P51858 |
0.72 |
|
MAP3K14 |
9020 |
Q99558 |
0.72 |
|
RRP1B |
23076 |
Q14684 |
0.72 |
|
SRPK3 |
26576 |
Q9UPE1 |
0.72 |
|
MRGBP |
55257 |
Q9NV56 |
0.72 |
|
CBX8 |
57332 |
Q9HC52 |
0.72 |
|
CNBP |
7555 |
P62633 |
0.76 |
|
HNRNPU |
3192 |
Q00839 |
0.82 |
|
NPM1 |
4869 |
P06748 |
0.82 |
|
RNF2 |
6045 |
Q99496 |
0.82 |
|
NOP56 |
10528 |
O00567 |
0.88 |