Protein Description

Gene Symbol GPSM1
Entrez ID 26086
Uniprot ID Q86YR5
Description G-protein signaling modulator 1
Chromosomal Location chr9: 136,327,476-136,359,605
Ontology GO ID GO Term Definition Evidence

BP

GO:0007399

nervous system development

The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

IEA

BP

GO:0008277

regulation of G-protein coupled receptor protein signaling pathway

Any process that modulates the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.

IEA

BP

GO:0030154

cell differentiation

The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

IEA

BP

GO:0050790

regulation of catalytic activity

Any process that modulates the activity of an enzyme.

IEA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

IEA

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

IEA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

IEA

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

IEA

MF

GO:0005092

GDP-dissociation inhibitor activity

Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding.

IEA

Domain ID Description

IPR003109

GoLoco motif

IPR011990

Tetratricopeptide-like helical domain

IPR013026

Tetratricopeptide repeat-containing domain

IPR019734

Tetratricopeptide repeat

IPR024804

G-protein-signalling modulator 1

Pathway ID Pathway Term Pathway Source

hsa05030

Cocaine addiction

KEGG

UMLS CUI UMLS Term

C0011860

Diabetes Mellitus, Non-Insulin-Dependent

C0236736

Cocaine-Related Disorders

Tissue Cell Type

heart muscle

myocytes

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

NUMA1

4926

Q14980

0.63

UGP2

7360

Q16851

0.63

RALBP1

10928

Q15311

0.63

KLHL18

23276

O94889

0.63

BRD4

23476

O60885

0.63

SAPCD2

89958

Q86UD0

0.63

USP9X

8239

Q93008

0.68

MAP1LC3A

84557

Q9H492

0.68

PPP6R3

55291

Q5H9R7

0.73

USHBP1

83878

Q8N6Y0

0.73

GPSM1

26086

Q86YR5

0.79

GNAI3

2773

P08754

0.85

INSC

387755

Q1MX18

0.52

TRIM23

373

P36406

0.63

CBS

875

P35520

0.63

GNAO1

2775

P09471

0.63

NTRK1

4914

P04629

0.63

XPO1

7514

O14980

0.63

CUL3

8452

Q13618

0.63

TRIP13

9319

Q15645

0.63

KANK2

25959

Q63ZY3

0.63

WDR83

84292

Q9BRX9

0.63

CCDC158

339965

Q5M9N0

0.63

ZBED1

9189

O96006

0.73

DAZAP2

9802

Q15038

0.73

OSTM1

28962

Q86WC4

0.75

GNAI1

2770

P63096

0.87