PCOSBase

Protein Description

Gene Symbol	UBXN7
Entrez ID	26043
Uniprot ID	O94888
Description	UBX domain protein 7
Chromosomal Location	chr3: 196,347,662-196,432,474

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Ontology	GO ID	GO Term	Definition	Evidence
CC	GO:0005654	nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.	IDA
CC	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry).	IDA
MF	GO:0005515	protein binding	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	IPI
MF	GO:0008134	transcription factor binding	Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.	IPI
MF	GO:0031625	ubiquitin protein ligase binding	Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.	IDA
MF	GO:0043130	ubiquitin binding	Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.	IDA

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Domain ID	Description
IPR001012	UBX domain
IPR006577	UAS
IPR009060	UBA-like
IPR012336	Thioredoxin-like fold
IPR017346	UBX domain-containing protein 2/7
IPR029071	Ubiquitin-related domain

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No pathways found.

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No diseases found.

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Tissue	Cell Type
epididymis	glandular cells
nasopharynx	respiratory epithelial cells
placenta	decidual cells
placenta	trophoblastic cells
thyroid gland	glandular cells

No databases found.

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Pubmed ID	Author	Year	Title
22951915	Haozi et al.	2012	Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

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Gene Symbol	Entrez ID	Uniprot ID	Score
ATP6V1B2	526	P21281	0.49
UCHL3	7347	P15374	0.49
ZYX	7791	Q15942	0.49
USP9X	8239	Q93008	0.49
ZPR1	8882	O75312	0.49
ATP6V1F	9296	Q16864	0.49
ZRANB2	9406	O95218	0.49
VPS26A	9559	O75436	0.49
YAP1	10413	P46937	0.49
UFC1	51506	Q9Y3C8	0.49
UFM1	51569	P61960	0.49
ZFYVE19	84936	Q96K21	0.49
APP	351	P05067	0.56
AMFR	267	Q9UKV5	0.63
ALPP	250	P05187	0.63
UBB	7314	P0CG47	0.63
PLAA	9373	Q9Y263	0.63
KLHDC2	23588	Q9Y2U9	0.63
KBTBD2	25948	Q8IY47	0.63
BIRC2	329	Q13490	0.72
SKP1	6500	P63208	0.72
TCEB2	6923	Q15370	0.72
UFD1L	7353	Q92890	0.72
VHL	7428	P40337	0.72
VPRBP	9730	Q9Y4B6	0.72
PJA2	9867	O43164	0.72
TOPORS	10210	Q9NS56	0.72
UBR2	23304	Q8IWV8	0.72
UBR4	23352	Q5T4S7	0.72
UBR5	51366	O95071	0.72
BRWD1	54014	Q9NSI6	0.72
WDR11	55717	Q9BZH6	0.72
KLHL12	59349	Q53G59	0.72
WDR26	80232	Q9H7D7	0.72
KBTBD7	84078	Q8WVZ9	0.72
KLHL22	84861	Q53GT1	0.72
KLHL13	90293	Q9P2N7	0.72
KLHDC3	116138	Q9BQ90	0.72
UBR1	197131	Q8IWV7	0.72
BRWD3	254065	Q6RI45	0.72
DDB1	100290337	Q16531	0.72
PSMD2	5708	Q13200	0.73
NPLOC4	55666	Q8TAT6	0.74
NEDD8	4738	Q15843	0.79
HIF1A	3091	Q16665	0.82
TCEB1	6921	Q15369	0.82
VCP	7415	P55072	0.82
CUL4B	8450	Q13620	0.82
CUL4A	8451	Q13619	0.82
CUL3	8452	Q13618	0.82
CUL1	8454	Q13616	0.82
RBX1	9978	P62877	0.82
CUL2	8453	Q13617	0.85
OXCT1	5019	P55809	0.49
RAD23B	5887	P54727	0.49
SULT1A1	6817	P50225	0.49
TYMS	7298	P04818	0.49
UBE2B	7320	P63146	0.49
UBE2D1	7321	P51668	0.49
UBE2D2	7322	P62837	0.49
UBE2L3	7332	P68036	0.49
UBE2V2	7336	Q15819	0.49
USP34	9736	Q70CQ2	0.49
NUBP2	10101	Q9Y5Y2	0.49
UBE4B	10277	O95155	0.49
SEC23A	10484	Q15436	0.49
SSSCA1	10534	O60232	0.49
UBE2C	11065	O00762	0.49
TTLL12	23170	Q14166	0.49
SDHAF2	54949	Q9NX18	0.49
SRXN1	140809	Q9BYN0	0.49
UBE2V1	387522	Q13404	0.49
MAP3K1	4214	Q13233	0.52
NTRK1	4914	P04629	0.63
LZTFL1	54585	Q9NQ48	0.63
DPP8	54878	Q6V1X1	0.63
NSUN2	54888	Q08J23	0.63
KCNK16	83795	Q96T55	0.63
SUMO2	6613	P61956	0.74