Gene Symbol | TENM4 |
Entrez ID | 26011 |
Uniprot ID | Q6N022 |
Description | teneurin transmembrane protein 4 |
Chromosomal Location | chr11: 78,652,831-79,440,948 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0000902 |
cell morphogenesis |
The developmental process in which the size or shape of a cell is generated and organized. |
IBA |
BP |
GO:0001702 |
gastrulation with mouth forming second |
A gastrulation process in which the initial invagination becomes the anus and the mouth forms second. |
IEA |
BP |
GO:0007157 |
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell. |
IBA |
BP |
GO:0007165 |
signal transduction |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
IEA |
BP |
GO:0031641 |
regulation of myelination |
Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons. |
IMP |
BP |
GO:0031643 |
positive regulation of myelination |
Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons. |
ISS |
BP |
GO:0032289 |
central nervous system myelin formation |
The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system. |
IMP|ISS |
BP |
GO:0048666 |
neuron development |
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. |
IMP |
BP |
GO:0048714 |
positive regulation of oligodendrocyte differentiation |
Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation. |
ISS |
BP |
GO:0060038 |
cardiac muscle cell proliferation |
The expansion of a cardiac muscle cell population by cell division. |
IEA |
BP |
GO:0060912 |
cardiac cell fate specification |
The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. |
IEA |
BP |
GO:0097264 |
self proteolysis |
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds. |
IEA |
BP |
GO:2000543 |
positive regulation of gastrulation |
Any process that activates or increases the frequency, rate or extent of gastrulation. |
ISS |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
ISS |
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
ISS |
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
IDA |
CC |
GO:0005887 |
integral component of plasma membrane |
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IBA |
CC |
GO:0043005 |
neuron projection |
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. |
IBA|ISS |
MF |
GO:0042803 |
protein homodimerization activity |
Interacting selectively and non-covalently with an identical protein to form a homodimer. |
IBA|ISS |
MF |
GO:0046982 |
protein heterodimerization activity |
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer. |
IBA |
MF |
GO:0050839 |
cell adhesion molecule binding |
Interacting selectively and non-covalently with a cell adhesion molecule. |
IBA |
Domain ID | Description |
---|---|
IPR000742 |
EGF-like domain |
IPR006530 |
YD repeat |
IPR008969 |
Carboxypeptidase-like, regulatory domain |
IPR009471 |
Teneurin intracellular, N-terminal |
IPR011042 |
Six-bladed beta-propeller, TolB-like |
IPR013032 |
EGF-like, conserved site |
IPR013111 |
EGF-like domain, extracellular |
IPR022385 |
Rhs repeat-associated core |
IPR027691 |
Teneurin-4 |
IPR028916 |
Tox-GHH domain |
UMLS CUI | UMLS Term |
---|---|
C0005586 |
Bipolar Disorder |
C0028754 |
Obesity |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
CAND1 |
55832 |
Q86VP6 |
0.63 |