Gene Symbol | DCAF13 |
Entrez ID | 25879 |
Uniprot ID | Q9NV06 |
Description | DDB1 and CUL4 associated factor 13 |
Chromosomal Location | chr8: 103,414,714-103,443,453 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0000462 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
IBA |
BP |
GO:0006364 |
rRNA processing |
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
TAS |
BP |
GO:0016567 |
protein ubiquitination |
The process in which one or more ubiquitin groups are added to a protein. |
IC|IEA |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
TAS |
CC |
GO:0005730 |
nucleolus |
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
IBA|IDA |
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
CC |
GO:0005813 |
centrosome |
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. |
IDA |
CC |
GO:0030054 |
cell junction |
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix. |
IDA |
CC |
GO:0032040 |
small-subunit processome |
A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins. |
IBA |
CC |
GO:0080008 |
Cul4-RING E3 ubiquitin ligase complex |
A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein. |
IDA |
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
Domain ID | Description |
---|---|
IPR001680 |
WD40 repeat |
IPR007287 |
Sof1-like protein |
IPR013979 |
Translation initiation factor, beta propellor-like domain |
IPR015943 |
WD40/YVTN repeat-like-containing domain |
IPR017986 |
WD40-repeat-containing domain |
IPR019775 |
WD40 repeat, conserved site |
Tissue | Cell Type |
---|---|
appendix |
glandular cells |
breast |
glandular cells |
bronchus |
respiratory epithelial cells |
cerebellum |
cells in granular layer |
colon |
glandular cells |
duodenum |
glandular cells |
esophagus |
squamous epithelial cells |
gallbladder |
glandular cells |
kidney |
cells in tubules |
nasopharynx |
respiratory epithelial cells |
rectum |
glandular cells |
skin |
keratinocytes |
skin |
epidermal cells |
small intestine |
glandular cells |
testis |
cells in seminiferous ducts |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
TBL3 |
10607 |
Q12788 |
0.49 |
UTP14A |
10813 |
Q9BVJ6 |
0.49 |
WDR36 |
134430 |
Q8NI36 |
0.49 |
FBL |
2091 |
P22087 |
0.49 |
IPO5 |
3843 |
O00410 |
0.49 |
DDX18 |
8886 |
Q9NVP1 |
0.49 |
RRP9 |
9136 |
O43818 |
0.49 |
POLR1C |
9533 |
O15160 |
0.49 |
PUM3 |
9933 |
Q15397 |
0.49 |
NOP56 |
10528 |
O00567 |
0.49 |
UTP20 |
27340 |
O75691 |
0.49 |
POLR1D |
51082 |
Q9Y2S0 |
0.49 |
DDX47 |
51202 |
Q9H0S4 |
0.49 |
NOP58 |
51602 |
Q9Y2X3 |
0.49 |
DDX27 |
55661 |
Q96GQ7 |
0.49 |
JUN |
3725 |
P05412 |
0.63 |
NEDD8 |
4738 |
Q15843 |
0.63 |
TK1 |
7083 |
P04183 |
0.63 |
SUMO1 |
7341 |
P63165 |
0.63 |
WARS |
7453 |
P23381 |
0.63 |
EED |
8726 |
O75530 |
0.63 |
UBD |
10537 |
O15205 |
0.63 |
PAXIP1 |
22976 |
Q6ZW49 |
0.63 |
SIRT7 |
51547 |
Q9NRC8 |
0.63 |
WDR83 |
84292 |
Q9BRX9 |
0.63 |
DDB1 |
100290337 |
Q16531 |
0.63 |
ATM |
472 |
Q13315 |
0.72 |
NDE1 |
54820 |
Q9NXR1 |
0.72 |
IFI16 |
3428 |
Q16666 |
0.82 |