PCOSBase

Protein Description

Ontology	GO ID	GO Term	Definition	Evidence
BP	GO:0005975	carbohydrate metabolic process	The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.	IEA
BP	GO:0006098	pentose-phosphate shunt	The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.	IDA\|IEA\|TAS
CC	GO:0005829	cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	TAS
CC	GO:0070062	extracellular exosome	A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.	IDA
MF	GO:0017057	6-phosphogluconolactonase activity	Catalysis of the reaction: 6-O-phosphono-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate + H(+).	EXP\|IDA

Domain ID	Description
IPR005900	6-phosphogluconolactonase, DevB-type
IPR006148	Glucosamine/galactosamine-6-phosphate isomerase

UMLS CUI	UMLS Term
C0029456	Osteoporosis

Tissue	Cell Type
adrenal gland	glandular cells
bone marrow	hematopoietic cells
breast	glandular cells
bronchus	respiratory epithelial cells
cervix, uterine	glandular cells
colon	glandular cells
duodenum	glandular cells
endometrium	cells in endometrial stroma
endometrium	glandular cells
fallopian tube	glandular cells
gallbladder	glandular cells
kidney	cells in glomeruli
kidney	cells in tubules
lymph node	non-germinal center cells
nasopharynx	respiratory epithelial cells
pancreas	exocrine glandular cells
pancreas	islets of Langerhans
placenta	decidual cells
rectum	glandular cells
seminal vesicle	glandular cells
skeletal muscle	myocytes
soft tissue	adipocytes
soft tissue	fibroblasts
spleen	cells in red pulp
spleen	cells in white pulp
testis	Leydig cells
thyroid gland	glandular cells
tonsil	non-germinal center cells

Pubmed ID	Author	Year	Title
22617121	Ouandaogo et al.	2012	Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol	Entrez ID	Uniprot ID	Score
TALDO1	6888	P37837	0.49
SSNA1	8636	O43805	0.49
IMPA1	3612	P29218	0.56
IMPA2	3613	O14732	0.56
RCHY1	25898	Q96PM5	0.63
KRTAP4-2	85291	Q9BYR5	0.63
KRT40	125115	Q6A162	0.63
KRTAP10-9	386676	P60411	0.63
KRTAP10-8	386681	P60410	0.63
KRTAP10-3	386682	P60369	0.63
NOTCH2NL	388677	Q7Z3S9	0.63
PEBP1	5037	P30086	0.56
KRTAP5-9	3846	P26371	0.63
KRT31	3881	Q15323	0.63
NTRK1	4914	P04629	0.63
SUMO2	6613	P61956	0.63
RBPMS	11030	Q93062	0.63
EWSR1	2130	Q01844	0.73
PLSCR1	5359	O15162	0.73
TERF1	7013	P54274	0.73
POT1	25913	Q9NUX5	0.73
TERF2IP	54386	Q9NYB0	0.75
MDFI	4188	Q99750	0.87