Gene Symbol | APOL2 |
Entrez ID | 23780 |
Uniprot ID | Q9BQE5 |
Description | apolipoprotein L2 |
Chromosomal Location | chr22: 36,226,203-36,239,954 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006629 |
lipid metabolic process |
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. |
NAS |
BP |
GO:0006869 |
lipid transport |
The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. |
NAS |
BP |
GO:0006953 |
acute-phase response |
An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals. |
NAS |
BP |
GO:0007275 |
multicellular organism development |
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). |
NAS |
BP |
GO:0008203 |
cholesterol metabolic process |
The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues. |
NAS |
BP |
GO:0042157 |
lipoprotein metabolic process |
The chemical reactions and pathways involving any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. |
IEA |
BP |
GO:0060135 |
maternal process involved in female pregnancy |
A reproductive process occurring in the mother that allows an embryo or fetus to develop within it. |
NAS |
CC |
GO:0005576 |
extracellular region |
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
IEA |
CC |
GO:0005789 |
endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. |
NAS |
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
MF |
GO:0005102 |
receptor binding |
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. |
NAS |
MF |
GO:0008035 |
high-density lipoprotein particle binding |
Interacting selectively and non-covalently with high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE. |
NAS |
MF |
GO:0008289 |
lipid binding |
Interacting selectively and non-covalently with a lipid. |
NAS |
Domain ID | Description |
---|---|
IPR008405 |
Apolipoprotein L |
UMLS CUI | UMLS Term |
---|---|
C0024809 |
Marijuana Abuse |
C0031391 |
Phencyclidine Abuse |
C0036341 |
Schizophrenia |
C0236736 |
Cocaine-Related Disorders |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
bone marrow |
hematopoietic cells |
cerebellum |
Purkinje cells |
cervix, uterine |
squamous epithelial cells |
fallopian tube |
glandular cells |
hippocampus |
neuronal cells |
kidney |
cells in glomeruli |
lung |
macrophages |
pancreas |
islets of Langerhans |
placenta |
decidual cells |
placenta |
trophoblastic cells |
stomach |
glandular cells |
testis |
Leydig cells |
tonsil |
squamous epithelial cells |
urinary bladder |
urothelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
UBB |
7314 |
P0CG47 |
0.63 |
FAM127A |
8933 |
A6ZKI3 |
0.63 |
FAM127A |
8933 |
O15255 |
0.63 |
BSG |
682 |
P35613 |
0.72 |
UBL4A |
8266 |
P11441 |
0.72 |
MAST3 |
23031 |
O60307 |
0.72 |
MRPS9 |
64965 |
P82933 |
0.72 |
TCTN3 |
26123 |
Q6NUS6 |
0.49 |
TCTN2 |
79867 |
Q96GX1 |
0.49 |
ALDH3B1 |
221 |
P43353 |
0.63 |
APBB2 |
323 |
Q92870 |
0.63 |
GNAZ |
2781 |
P19086 |
0.63 |
PSG9 |
5678 |
Q00887 |
0.63 |
STX1A |
6804 |
Q16623 |
0.63 |
TMEM30A |
55754 |
Q9NV96 |
0.63 |
STX1B |
112755 |
P61266 |
0.63 |
EID3 |
493861 |
Q8N140 |
0.63 |
AR |
367 |
P10275 |
0.65 |
NCBP1 |
4686 |
Q09161 |
0.72 |
MAPK3 |
5595 |
P27361 |
0.72 |
POLK |
51426 |
Q9UBT6 |
0.72 |
TMEM63B |
55362 |
Q5T3F8 |
0.72 |
CERK |
64781 |
Q8TCT0 |
0.72 |